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  • 11.0 [archived version]
STRINGSTRING
CTDSP1 CTDSP1 BRD9 BRD9 NINJ1 NINJ1 ROPN1L ROPN1L CATIP CATIP HSPB6 HSPB6 NANP NANP TTC17 TTC17 FN3K FN3K TBC1D21 TBC1D21 PNKD PNKD
"CATIP" - Ciliogenesis-associated TTC17-interacting protein in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CATIPCiliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization (387 aa)    
Predicted Functional Partners:
TBC1D21
TBC1 domain family member 21; May act as a GTPase-activating protein for Rab family protein(s). May be involved in acrosome formation and cytoskeletal reorganization during spermiogenesis, possibly by regulating RAB3A activity (336 aa)
           
  0.814
TTC17
Tetratricopeptide repeat protein 17; Plays a role in primary ciliogenesis by modulating actin polymerization; Tetratricopeptide repeat domain containing (1141 aa)
           
  0.755
PNKD
Probable hydrolase PNKD; Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa- B signaling pathway; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family (385 aa)
           
  0.727
NANP
N-acylneuraminate-9-phosphatase; Haloacid dehalogenase like hydrolase domain containing; HAD Asp-based non-protein phosphatases (248 aa)
           
  0.681
FN3K
Fructosamine-3-kinase; May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme (309 aa)
           
  0.652
CTDSP1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Preferentially catalyzes the dephosphorylation of ’Ser- 5’ within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells; CTD family phosphatases (261 aa)
     
   
  0.633
HSPB6
Heat shock protein beta-6; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity (160 aa)
           
  0.613
ROPN1L
Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation (230 aa)
     
   
  0.607
NINJ1
Ninjurin-1; Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations (152 aa)
           
  0.576
BRD9
Bromodomain-containing protein 9; Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones- binds histones that are acetylated and/or butyrylated; BAF complex (597 aa)
       
      0.552
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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