• Version:
  • 11.0 [archived version]
STRINGSTRING
OR4X2 OR4X2 OR10A3 OR10A3 DCP1B DCP1B CHERP CHERP ACTA2 ACTA2 C9orf43 C9orf43 DENND4B DENND4B FRMPD3 FRMPD3 OR7D2 OR7D2 KIAA2018 KIAA2018 OR2AT4 OR2AT4
"C9orf43" - Uncharacterized protein C9orf43 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C9orf43Uncharacterized protein C9orf43; Chromosome 9 open reading frame 43 (461 aa)    
Predicted Functional Partners:
OR4X2
Olfactory receptor 4X2; Odorant receptor; Olfactory receptors, family 4 (303 aa)
           
  0.670
OR7D2
Olfactory receptor 7D2; Odorant receptor; Olfactory receptors, family 7 (312 aa)
           
  0.659
ACTA2
Actin, aortic smooth muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family (377 aa)
       
      0.638
KIAA2018
Basic helix-loop-helix domain-containing protein USF3; Involved in the negative regulation of epithelial- mesenchymal transition, the process by which epithelial cells lose their polarity and adhesion properties to become mesenchymal cells with enhanced migration and invasive properties (2245 aa)
           
  0.596
DENND4B
DENN domain-containing protein 4B; Guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form; DENN/MADD domain containing (1496 aa)
           
  0.592
OR10A3
Olfactory receptor 10A3; Odorant receptor; Olfactory receptors, family 10 (314 aa)
           
  0.582
FRMPD3
FERM and PDZ domain containing 3 (1810 aa)
           
  0.564
CHERP
Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing (916 aa)
           
  0.559
OR2AT4
Olfactory receptor 2AT4; Odorant receptor; Olfactory receptors, family 2 (320 aa)
           
  0.555
DCP1B
mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5’-phosphorylated mRNA fragment and 7m-GDP (By similarity) (617 aa)
           
  0.542
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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