FAM81A protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FAM81A

Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family (368 aa)

Predicted Functional Partners:

GCNT4

0.712

TMED6

0.671

GCNT3

0.665

FAM135A

0.662

GCNT1

0.651

CHAC2

0.603

FAM189A1

0.593

FAM171B

0.593

TMEM179

0.584

TMEM88B

0.569

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHAC2	FAM135A	ENSP00000295304	ENSP00000410768	Glutathione-specific gamma-glutamylcyclotransferase 2; Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family	0.600
CHAC2	FAM81A	ENSP00000295304	ENSP00000288228	Glutathione-specific gamma-glutamylcyclotransferase 2; Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	0.603
CHAC2	TMED6	ENSP00000295304	ENSP00000288025	Glutathione-specific gamma-glutamylcyclotransferase 2; Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	Transmembrane p24 trafficking protein 6	0.579
FAM135A	CHAC2	ENSP00000410768	ENSP00000295304	Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family	Glutathione-specific gamma-glutamylcyclotransferase 2; Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	0.600
FAM135A	FAM81A	ENSP00000410768	ENSP00000288228	Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	0.662
FAM135A	TMED6	ENSP00000410768	ENSP00000288025	Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family	Transmembrane p24 trafficking protein 6	0.643
FAM171B	FAM189A1	ENSP00000304108	ENSP00000261275	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family	0.674
FAM171B	FAM81A	ENSP00000304108	ENSP00000288228	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	0.593
FAM171B	TMEM179	ENSP00000304108	ENSP00000450958	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Transmembrane protein 179; Belongs to the TMEM179 family	0.642
FAM171B	TMEM88B	ENSP00000304108	ENSP00000455099	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Transmembrane protein 88B	0.631
FAM189A1	FAM171B	ENSP00000261275	ENSP00000304108	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	0.674
FAM189A1	FAM81A	ENSP00000261275	ENSP00000288228	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	0.593
FAM189A1	TMEM179	ENSP00000261275	ENSP00000450958	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family	Transmembrane protein 179; Belongs to the TMEM179 family	0.683
FAM189A1	TMEM88B	ENSP00000261275	ENSP00000455099	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family	Transmembrane protein 88B	0.617
FAM81A	CHAC2	ENSP00000288228	ENSP00000295304	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	Glutathione-specific gamma-glutamylcyclotransferase 2; Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	0.603
FAM81A	FAM135A	ENSP00000288228	ENSP00000410768	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family	0.662
FAM81A	FAM171B	ENSP00000288228	ENSP00000304108	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	0.593
FAM81A	FAM189A1	ENSP00000288228	ENSP00000261275	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family	0.593
FAM81A	GCNT1	ENSP00000288228	ENSP00000415454	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes; Glucosaminyl transferases/xylosyltransferases	0.651
FAM81A	GCNT3	ENSP00000288228	ENSP00000379377	Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development	0.665

page 1 of 3

Network

Cooccurrence

Databases

Coexpression

Textmining

Neighborhood

Experiments

Fusion

© STRING Consortium 2020

Credits

Access

Info

About