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STRINGSTRING
OXSM OXSM COX18 COX18 PTGR2 PTGR2 ALG2 ALG2 MGST3 MGST3 C1orf226 C1orf226 DHRS1 DHRS1 DHRSX DHRSX SDPR SDPR RDH10 RDH10 GLOD4 GLOD4
"DHRS1" - Dehydrogenase/reductase SDR family member 1 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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DHRS1Dehydrogenase/reductase SDR family member 1; Short chain dehydrogenase/reductase superfamily; Belongs to the short-chain dehydrogenases/reductases (SDR) family (313 aa)    
Predicted Functional Partners:
SDPR
Caveolae-associated protein 2; Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae (By similarity) (425 aa)
            
  0.904
C1orf226
Uncharacterized protein C1orf226; Chromosome 1 open reading frame 226 (315 aa)
            
  0.585
ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2; Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily (416 aa)
  
 
   
  0.523
PTGR2
Prostaglandin reductase 2; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity) (351 aa)
      
   
  0.514
DHRSX
Dehydrogenase/reductase SDR family member on chromosome X; Involved in the positive regulation of starvation- induced autophagy; Belongs to the short-chain dehydrogenases/reductases (SDR) family (330 aa)
        
 
  0.497
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function; Belongs to the beta-ketoacyl-ACP synthases family (459 aa)
   
 
  0.496
MGST3
Microsomal glutathione S-transferase 3; Also functions as a glutathione peroxidase; Microsomal glutathione S-transferases (152 aa)
            
  0.495
GLOD4
Glyoxalase domain containing 4 (298 aa)
      
   
  0.494
COX18
Mitochondrial inner membrane protein COX18; Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space; Mitochondrial respiratory chain complex assembly factors (334 aa)
      
   
  0.485
RDH10
Retinol dehydrogenase 10; Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol; Short chain dehydrogenase/reductase superfamily (341 aa)
            
  0.483
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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