FUK protein (human) - STRING database

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FUK

L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides (1084 aa)

Predicted Functional Partners:

FPGT

0.941

TSTA3

0.874

GMDS

0.854

HKDC1

0.827

HK1

0.818

HK2

0.818

HK3

0.815

SORD

0.808

KHK

0.800

FUCA2

0.681

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FPGT	FUCA2	ENSP00000359935	ENSP00000002165	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	Plasma alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family	0.486
FPGT	FUK	ENSP00000359935	ENSP00000288078	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	0.941
FPGT	GMDS	ENSP00000359935	ENSP00000370194	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily	0.741
FPGT	TSTA3	ENSP00000359935	ENSP00000398803	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Short chain dehydrogenase/reductase superfamily	0.979
FUCA2	FPGT	ENSP00000002165	ENSP00000359935	Plasma alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	0.486
FUCA2	FUK	ENSP00000002165	ENSP00000288078	Plasma alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	0.681
FUCA2	TSTA3	ENSP00000002165	ENSP00000398803	Plasma alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family	GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Short chain dehydrogenase/reductase superfamily	0.414
FUK	FPGT	ENSP00000288078	ENSP00000359935	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	0.941
FUK	FUCA2	ENSP00000288078	ENSP00000002165	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	Plasma alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family	0.681
FUK	GMDS	ENSP00000288078	ENSP00000370194	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily	0.854
FUK	HK1	ENSP00000288078	ENSP00000402103	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	Hexokinase-1; Hexokinase 1	0.818
FUK	HK2	ENSP00000288078	ENSP00000290573	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	Hexokinase-2; Hexokinase 2; Belongs to the hexokinase family	0.818
FUK	HK3	ENSP00000288078	ENSP00000292432	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	Hexokinase-3; Hexokinase 3	0.815
FUK	HKDC1	ENSP00000288078	ENSP00000346643	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	Putative hexokinase HKDC1; Hexokinase domain containing 1	0.827
FUK	KHK	ENSP00000288078	ENSP00000260599	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	Ketohexokinase; Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate; Belongs to the carbohydrate kinase PfkB family	0.800
FUK	SORD	ENSP00000288078	ENSP00000267814	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	Sorbitol dehydrogenase; Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm; Belongs to the zinc-containing alcohol dehydrogenase family	0.808
FUK	TSTA3	ENSP00000288078	ENSP00000398803	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Short chain dehydrogenase/reductase superfamily	0.874
GMDS	FPGT	ENSP00000370194	ENSP00000359935	GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	0.741
GMDS	FUK	ENSP00000370194	ENSP00000288078	GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily	L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides	0.854
GMDS	TSTA3	ENSP00000370194	ENSP00000398803	GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily	GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Short chain dehydrogenase/reductase superfamily	0.999

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