NOMO1 protein (human) - STRING database

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NOMO1

Nodal modulator 1; May antagonize Nodal signaling (1222 aa)

Predicted Functional Partners:

PDXDC1

0.903

NCLN

0.872

BFAR

0.753

TMEM147

0.563

MLLT3

0.554

UPF2

0.549

EXOSC10

0.547

TMEM120A

0.527

ARL15

0.527

TMEM120B

0.527

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL15	NCLN	ENSP00000433427	ENSP00000246117	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	0.527
ARL15	NOMO1	ENSP00000433427	ENSP00000287667	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	Nodal modulator 1; May antagonize Nodal signaling	0.527
ARL15	TMEM120A	ENSP00000433427	ENSP00000473983	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.527
ARL15	TMEM120B	ENSP00000433427	ENSP00000404991	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	Transmembrane protein 120B; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.527
BFAR	NOMO1	ENSP00000261658	ENSP00000287667	Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors; Ring finger proteins	Nodal modulator 1; May antagonize Nodal signaling	0.753
BFAR	PDXDC1	ENSP00000261658	ENSP00000379691	Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors; Ring finger proteins	Pyridoxal-dependent decarboxylase domain-containing protein 1; Pyridoxal dependent decarboxylase domain containing 1; Belongs to the group II decarboxylase family	0.905
EXOSC10	NOMO1	ENSP00000366135	ENSP00000287667	Exosome component 10; Putative catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...]	Nodal modulator 1; May antagonize Nodal signaling	0.547
EXOSC10	UPF2	ENSP00000366135	ENSP00000348708	Exosome component 10; Putative catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...]	Regulator of nonsense transcripts 2; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA	0.861
MLLT3	NOMO1	ENSP00000369695	ENSP00000287667	Protein AF-9; Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Recognizes and binds histone H3 crotonylated at ’Lys-9’ (H3K9cr), and with slightly lower affinity histone H3 crotonylate [...]	Nodal modulator 1; May antagonize Nodal signaling	0.554
NCLN	ARL15	ENSP00000246117	ENSP00000433427	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	0.527
NCLN	NOMO1	ENSP00000246117	ENSP00000287667	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	Nodal modulator 1; May antagonize Nodal signaling	0.872
NCLN	TMEM120A	ENSP00000246117	ENSP00000473983	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.723
NCLN	TMEM120B	ENSP00000246117	ENSP00000404991	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	Transmembrane protein 120B; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.527
NCLN	TMEM147	ENSP00000246117	ENSP00000222284	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	Transmembrane protein 147	0.985
NOMO1	ARL15	ENSP00000287667	ENSP00000433427	Nodal modulator 1; May antagonize Nodal signaling	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	0.527
NOMO1	BFAR	ENSP00000287667	ENSP00000261658	Nodal modulator 1; May antagonize Nodal signaling	Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors; Ring finger proteins	0.753
NOMO1	EXOSC10	ENSP00000287667	ENSP00000366135	Nodal modulator 1; May antagonize Nodal signaling	Exosome component 10; Putative catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...]	0.547
NOMO1	MLLT3	ENSP00000287667	ENSP00000369695	Nodal modulator 1; May antagonize Nodal signaling	Protein AF-9; Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Recognizes and binds histone H3 crotonylated at ’Lys-9’ (H3K9cr), and with slightly lower affinity histone H3 crotonylate [...]	0.554
NOMO1	NCLN	ENSP00000287667	ENSP00000246117	Nodal modulator 1; May antagonize Nodal signaling	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	0.872
NOMO1	PDXDC1	ENSP00000287667	ENSP00000379691	Nodal modulator 1; May antagonize Nodal signaling	Pyridoxal-dependent decarboxylase domain-containing protein 1; Pyridoxal dependent decarboxylase domain containing 1; Belongs to the group II decarboxylase family	0.903

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