node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FBXL18 | PTP4A1 | ENSP00000371805 | ENSP00000359685 | F-box/LRR-repeat protein 18; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | Protein tyrosine phosphatase type IVA 1; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis | 0.666 |
FBXL18 | RPS27A | ENSP00000371805 | ENSP00000272317 | F-box/LRR-repeat protein 18; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | Ubiquitin-40S ribosomal protein S27a; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be inv [...] | 0.900 |
FBXL18 | TRIM36 | ENSP00000371805 | ENSP00000282369 | F-box/LRR-repeat protein 18; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | E3 ubiquitin-protein ligase TRIM36; E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization; Belongs to the TRIM/RBCC family | 0.900 |
FBXL18 | UBA52 | ENSP00000371805 | ENSP00000388107 | F-box/LRR-repeat protein 18; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | Ubiquitin-60S ribosomal protein L40; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be invo [...] | 0.900 |
FBXL18 | ZFAND3 | ENSP00000371805 | ENSP00000287218 | F-box/LRR-repeat protein 18; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | Zinc finger AN1-type containing 3 | 0.724 |
FITM2 | GCC1 | ENSP00000380037 | ENSP00000318821 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | 0.642 |
FITM2 | KCNK16 | ENSP00000380037 | ENSP00000391498 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | 0.649 |
FITM2 | R3HDML | ENSP00000380037 | ENSP00000217043 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | Peptidase inhibitor R3HDML; Putative serine protease inhibitor; CAP superfamily | 0.703 |
FITM2 | ZFAND3 | ENSP00000380037 | ENSP00000287218 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | Zinc finger AN1-type containing 3 | 0.669 |
FOXQ1 | ZFAND3 | ENSP00000296839 | ENSP00000287218 | Forkhead box protein Q1; Plays a role in hair follicle differentiation; Forkhead boxes | Zinc finger AN1-type containing 3 | 0.662 |
GCC1 | FITM2 | ENSP00000318821 | ENSP00000380037 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | 0.642 |
GCC1 | KCNK16 | ENSP00000318821 | ENSP00000391498 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | 0.669 |
GCC1 | R3HDML | ENSP00000318821 | ENSP00000217043 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Peptidase inhibitor R3HDML; Putative serine protease inhibitor; CAP superfamily | 0.672 |
GCC1 | ZFAND3 | ENSP00000318821 | ENSP00000287218 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Zinc finger AN1-type containing 3 | 0.669 |
KCNK16 | FITM2 | ENSP00000391498 | ENSP00000380037 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | 0.649 |
KCNK16 | GCC1 | ENSP00000391498 | ENSP00000318821 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | 0.669 |
KCNK16 | R3HDML | ENSP00000391498 | ENSP00000217043 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Peptidase inhibitor R3HDML; Putative serine protease inhibitor; CAP superfamily | 0.673 |
KCNK16 | ZFAND3 | ENSP00000391498 | ENSP00000287218 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Zinc finger AN1-type containing 3 | 0.674 |
PTP4A1 | FBXL18 | ENSP00000359685 | ENSP00000371805 | Protein tyrosine phosphatase type IVA 1; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis | F-box/LRR-repeat protein 18; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | 0.666 |
PTP4A1 | ZFAND3 | ENSP00000359685 | ENSP00000287218 | Protein tyrosine phosphatase type IVA 1; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis | Zinc finger AN1-type containing 3 | 0.700 |