• Version:
  • 11.0 [archived version]
STRINGSTRING
MESDC1 MESDC1 TMC3 TMC3 ACTRT2 ACTRT2 USP36 USP36 ACTRT3 ACTRT3 C15orf26 C15orf26 ERICH1 ERICH1 UTP15 UTP15 IL16 IL16 MYCBPAP MYCBPAP WSCD1 WSCD1
"C15orf26" - Cilia- and flagella-associated protein 161 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
C15orf26Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly (301 aa)    
Predicted Functional Partners:
MESDC1
Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells (362 aa)
           
  0.730
USP36
Ubiquitin carboxyl-terminal hydrolase 36; May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 ’Lys-4’ trimethylation (H3K4) (By similarity); Belongs to the peptidase C19 family (1123 aa)
     
   
  0.694
TMC3
Transmembrane channel-like protein 3; Probable ion channel; Transmembrane channel likes (1100 aa)
           
  0.659
WSCD1
WSC domain containing 1 (575 aa)
           
  0.623
IL16
Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4; Interleukins (1332 aa)
 
       
  0.591
ACTRT3
Actin related protein T3 (372 aa)
     
   
  0.563
ACTRT2
Actin related protein T2 (377 aa)
     
   
  0.546
UTP15
U3 small nucleolar RNA-associated protein 15 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre- ribosomal RNA transcription by RNA polymerase I; UTPa subcomplex (518 aa)
           
  0.543
ERICH1
Glutamate-rich protein 1; Glutamate rich 1 (443 aa)
           
  0.543
MYCBPAP
MYCBP-associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) (984 aa)
           
  0.530
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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