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  • 11.0 [archived version]
STRINGSTRING
BLOC1S5 BLOC1S5 SPCS1 SPCS1 GPR142 GPR142 GPR26 GPR26 GPR20 GPR20 PCP4L1 PCP4L1 GPR82 GPR82 GPR162 GPR162 GPR101 GPR101 GAST GAST GPR62 GPR62
"GPR26" - G-protein coupled receptor 26 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
GPR26G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP; G protein-coupled receptors, Class A orphans (337 aa)    
Predicted Functional Partners:
GAST
Gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine; Endogenous ligands (101 aa)
           
  0.641
GPR20
G-protein coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP; G protein-coupled receptors, Class A orphans (358 aa)
           
  0.614
GPR62
Probable G-protein coupled receptor 62; Orphan receptor; G protein-coupled receptors, Class A orphans (368 aa)
     
   
  0.576
PCP4L1
Purkinje cell protein 4 like 1; Belongs to the PCP4 family (68 aa)
     
   
  0.566
GPR101
Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans (508 aa)
     
   
  0.565
GPR82
Probable G-protein coupled receptor 82; Orphan receptor; G protein-coupled receptors, Class A orphans (336 aa)
           
  0.561
GPR162
Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans (588 aa)
     
   
  0.554
GPR142
Probable G-protein coupled receptor 142; Orphan receptor; G protein-coupled receptors, Class A orphans (462 aa)
           
  0.551
BLOC1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking; Belongs to th [...] (187 aa)
           
  0.548
SPCS1
Signal peptidase complex subunit 1; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum; Belongs to the SPCS1 family (169 aa)
           
  0.544
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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