node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C3orf52 | C4orf19 | ENSP00000399392 | ENSP00000284437 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | 0.581 |
C4orf19 | C3orf52 | ENSP00000284437 | ENSP00000399392 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52 | 0.581 |
C4orf19 | CORO1C | ENSP00000284437 | ENSP00000394496 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Coronin-1C; May be involved in cytokinesis, motility, and signal transduction; Belongs to the WD repeat coronin family | 0.682 |
C4orf19 | FAM219B | ENSP00000284437 | ENSP00000350260 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Protein FAM219B; Family with sequence similarity 219 member B | 0.590 |
C4orf19 | FAM221A | ENSP00000284437 | ENSP00000342576 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Protein FAM221A; Family with sequence similarity 221 member A; Belongs to the FAM221 family | 0.588 |
C4orf19 | ISM1 | ENSP00000284437 | ENSP00000262487 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Isthmin-1; Acts as an angiogenesis inhibitor; Belongs to the isthmin family | 0.677 |
C4orf19 | KATNBL1 | ENSP00000284437 | ENSP00000256544 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro | 0.546 |
C4orf19 | MST4 | ENSP00000284437 | ENSP00000377867 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Serine/threonine-protein kinase 26; Mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily | 0.836 |
C4orf19 | PDCD10 | ENSP00000284437 | ENSP00000376506 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity); Belongs to the PDCD10 family | 0.860 |
C4orf19 | STK24 | ENSP00000284437 | ENSP00000365730 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Serine/threonine-protein kinase 24; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress- induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase- independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on ’Thr-442’ and sti [...] | 0.864 |
C4orf19 | STK25 | ENSP00000284437 | ENSP00000325748 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration | 0.826 |
CORO1C | C4orf19 | ENSP00000394496 | ENSP00000284437 | Coronin-1C; May be involved in cytokinesis, motility, and signal transduction; Belongs to the WD repeat coronin family | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | 0.682 |
CORO1C | ISM1 | ENSP00000394496 | ENSP00000262487 | Coronin-1C; May be involved in cytokinesis, motility, and signal transduction; Belongs to the WD repeat coronin family | Isthmin-1; Acts as an angiogenesis inhibitor; Belongs to the isthmin family | 0.507 |
FAM219B | C4orf19 | ENSP00000350260 | ENSP00000284437 | Protein FAM219B; Family with sequence similarity 219 member B | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | 0.590 |
FAM219B | FAM221A | ENSP00000350260 | ENSP00000342576 | Protein FAM219B; Family with sequence similarity 219 member B | Protein FAM221A; Family with sequence similarity 221 member A; Belongs to the FAM221 family | 0.558 |
FAM219B | KATNBL1 | ENSP00000350260 | ENSP00000256544 | Protein FAM219B; Family with sequence similarity 219 member B | KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro | 0.510 |
FAM221A | C4orf19 | ENSP00000342576 | ENSP00000284437 | Protein FAM221A; Family with sequence similarity 221 member A; Belongs to the FAM221 family | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | 0.588 |
FAM221A | FAM219B | ENSP00000342576 | ENSP00000350260 | Protein FAM221A; Family with sequence similarity 221 member A; Belongs to the FAM221 family | Protein FAM219B; Family with sequence similarity 219 member B | 0.558 |
FAM221A | KATNBL1 | ENSP00000342576 | ENSP00000256544 | Protein FAM221A; Family with sequence similarity 221 member A; Belongs to the FAM221 family | KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro | 0.493 |
ISM1 | C4orf19 | ENSP00000262487 | ENSP00000284437 | Isthmin-1; Acts as an angiogenesis inhibitor; Belongs to the isthmin family | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | 0.677 |