node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCA6 | ABCC3 | ENSP00000284425 | ENSP00000285238 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | 0.494 |
ABCA6 | ABCD4 | ENSP00000284425 | ENSP00000349396 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm; ATP binding cassette subfamily D | 0.532 |
ABCA6 | ABCF1 | ENSP00000284425 | ENSP00000313603 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | 0.474 |
ABCA6 | ABCF3 | ENSP00000284425 | ENSP00000411471 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F | 0.605 |
ABCA6 | CDAN1 | ENSP00000284425 | ENSP00000348564 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | Codanin-1; May act as a negative regulator of ASF1 in chromatin assembly | 0.451 |
ABCA6 | DCAF4L1 | ENSP00000284425 | ENSP00000327796 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | DDB1- and CUL4-associated factor 4-like protein 1; DDB1 and CUL4 associated factor 4 like 1; WD repeat domain containing | 0.440 |
ABCA6 | FABP12 | ENSP00000284425 | ENSP00000353650 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family | 0.474 |
ABCA6 | MAP2K6 | ENSP00000284425 | ENSP00000468348 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 i [...] | 0.469 |
ABCA6 | SLC22A8 | ENSP00000284425 | ENSP00000337335 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | Solute carrier family 22 member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA); Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | 0.550 |
ABCA6 | SRRM1 | ENSP00000284425 | ENSP00000326261 | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | Serine/arginine repetitive matrix protein 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3’-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with lo [...] | 0.554 |
ABCC3 | ABCA6 | ENSP00000285238 | ENSP00000284425 | Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | 0.494 |
ABCC3 | ABCF1 | ENSP00000285238 | ENSP00000313603 | Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | 0.401 |
ABCC3 | ABCF3 | ENSP00000285238 | ENSP00000411471 | Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F | 0.523 |
ABCC3 | SLC22A8 | ENSP00000285238 | ENSP00000337335 | Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | Solute carrier family 22 member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA); Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | 0.553 |
ABCD4 | ABCA6 | ENSP00000349396 | ENSP00000284425 | ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm; ATP binding cassette subfamily D | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | 0.532 |
ABCD4 | ABCF1 | ENSP00000349396 | ENSP00000313603 | ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm; ATP binding cassette subfamily D | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | 0.606 |
ABCD4 | ABCF3 | ENSP00000349396 | ENSP00000411471 | ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm; ATP binding cassette subfamily D | ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F | 0.724 |
ABCF1 | ABCA6 | ENSP00000313603 | ENSP00000284425 | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family | 0.474 |
ABCF1 | ABCC3 | ENSP00000313603 | ENSP00000285238 | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | 0.401 |
ABCF1 | ABCD4 | ENSP00000313603 | ENSP00000349396 | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm; ATP binding cassette subfamily D | 0.606 |