GPR115 protein (human) - STRING database

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GPR115

Adhesion G protein-coupled receptor F4; Orphan receptor (695 aa)

Predicted Functional Partners:

WFDC5

0.683

GPR123

0.657

C5orf46

0.654

MUM1

0.620

LRRC46

0.576

GXYLT2

0.576

SERPINB7

0.574

TXNDC9

0.552

ZNF530

0.543

GPR125

0.541

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5orf46	GPR115	ENSP00000315370	ENSP00000283303	Uncharacterized protein C5orf46; Chromosome 5 open reading frame 46	Adhesion G protein-coupled receptor F4; Orphan receptor	0.654
C5orf46	SERPINB7	ENSP00000315370	ENSP00000381101	Uncharacterized protein C5orf46; Chromosome 5 open reading frame 46	Serpin B7; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin; Serpin peptidase inhibitors	0.492
C5orf46	WFDC5	ENSP00000315370	ENSP00000361875	Uncharacterized protein C5orf46; Chromosome 5 open reading frame 46	WAP four-disulfide core domain protein 5; Putative acid-stable proteinase inhibitor; WAP four-disulfide core domain containing	0.549
GPR115	C5orf46	ENSP00000283303	ENSP00000315370	Adhesion G protein-coupled receptor F4; Orphan receptor	Uncharacterized protein C5orf46; Chromosome 5 open reading frame 46	0.654
GPR115	GPR123	ENSP00000283303	ENSP00000376384	Adhesion G protein-coupled receptor F4; Orphan receptor	Adhesion G protein-coupled receptor A1; Orphan receptor	0.657
GPR115	GPR125	ENSP00000283303	ENSP00000334952	Adhesion G protein-coupled receptor F4; Orphan receptor	Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.541
GPR115	GXYLT2	ENSP00000283303	ENSP00000374268	Adhesion G protein-coupled receptor F4; Orphan receptor	Glucoside xylosyltransferase 2; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose; Glycosyltransferase family 8	0.576
GPR115	LRRC46	ENSP00000283303	ENSP00000269025	Adhesion G protein-coupled receptor F4; Orphan receptor	Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46	0.576
GPR115	MUM1	ENSP00000283303	ENSP00000467083	Adhesion G protein-coupled receptor F4; Orphan receptor	PWWP domain-containing protein MUM1; Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage; PWWP domain containing	0.620
GPR115	SERPINB7	ENSP00000283303	ENSP00000381101	Adhesion G protein-coupled receptor F4; Orphan receptor	Serpin B7; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin; Serpin peptidase inhibitors	0.574
GPR115	TXNDC9	ENSP00000283303	ENSP00000264255	Adhesion G protein-coupled receptor F4; Orphan receptor	Thioredoxin domain-containing protein 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin	0.552
GPR115	WFDC5	ENSP00000283303	ENSP00000361875	Adhesion G protein-coupled receptor F4; Orphan receptor	WAP four-disulfide core domain protein 5; Putative acid-stable proteinase inhibitor; WAP four-disulfide core domain containing	0.683
GPR115	ZNF530	ENSP00000283303	ENSP00000332861	Adhesion G protein-coupled receptor F4; Orphan receptor	Zinc finger protein 530; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.543
GPR123	GPR115	ENSP00000376384	ENSP00000283303	Adhesion G protein-coupled receptor A1; Orphan receptor	Adhesion G protein-coupled receptor F4; Orphan receptor	0.657
GPR125	GPR115	ENSP00000334952	ENSP00000283303	Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Adhesion G protein-coupled receptor F4; Orphan receptor	0.541
GXYLT2	GPR115	ENSP00000374268	ENSP00000283303	Glucoside xylosyltransferase 2; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose; Glycosyltransferase family 8	Adhesion G protein-coupled receptor F4; Orphan receptor	0.576
GXYLT2	MUM1	ENSP00000374268	ENSP00000467083	Glucoside xylosyltransferase 2; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose; Glycosyltransferase family 8	PWWP domain-containing protein MUM1; Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage; PWWP domain containing	0.619
GXYLT2	TXNDC9	ENSP00000374268	ENSP00000264255	Glucoside xylosyltransferase 2; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose; Glycosyltransferase family 8	Thioredoxin domain-containing protein 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin	0.497
LRRC46	GPR115	ENSP00000269025	ENSP00000283303	Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46	Adhesion G protein-coupled receptor F4; Orphan receptor	0.576
MUM1	GPR115	ENSP00000467083	ENSP00000283303	PWWP domain-containing protein MUM1; Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage; PWWP domain containing	Adhesion G protein-coupled receptor F4; Orphan receptor	0.620

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