CCDC148 protein (human) - STRING database

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CCDC148

Coiled-coil domain containing 148 (591 aa)

Predicted Functional Partners:

LRRC49

0.768

CCDC181

0.751

UPP2

0.586

CDH26

0.581

RPAP2

0.500

SLC47A2

0.480

PPP1R32

0.473

GALNT13

0.472

ZNF821

0.472

TMEM186

0.449

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC148	CCDC181	ENSP00000283233	ENSP00000356780	Coiled-coil domain containing 148	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	0.751
CCDC148	CDH26	ENSP00000283233	ENSP00000339390	Coiled-coil domain containing 148	Cadherin-like protein 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	0.581
CCDC148	GALNT13	ENSP00000283233	ENSP00000376570	Coiled-coil domain containing 148	Polypeptide N-acetylgalactosaminyltransferase 13; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a much stronger activity than GALNT1 to transfer GalNAc to mucin peptides, such as Muc5Ac and Muc7. Able to glycosylate SDC3. May be responsible for the synthesis of Tn antigen in neuronal cells; Polypeptide N-acetylgalactosaminyltransferases	0.472
CCDC148	LRRC49	ENSP00000283233	ENSP00000453273	Coiled-coil domain containing 148	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	0.768
CCDC148	PPP1R32	ENSP00000283233	ENSP00000344140	Coiled-coil domain containing 148	Protein phosphatase 1 regulatory subunit 32	0.473
CCDC148	RPAP2	ENSP00000283233	ENSP00000476948	Coiled-coil domain containing 148	Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes	0.500
CCDC148	SLC47A2	ENSP00000283233	ENSP00000326671	Coiled-coil domain containing 148	Multidrug and toxin extrusion protein 2; Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes	0.480
CCDC148	TMEM186	ENSP00000283233	ENSP00000331640	Coiled-coil domain containing 148	Transmembrane protein 186	0.449
CCDC148	UPP2	ENSP00000283233	ENSP00000474090	Coiled-coil domain containing 148	Uridine phosphorylase 2; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(’)-deoxyuridine as substrates	0.586
CCDC148	ZNF821	ENSP00000283233	ENSP00000398089	Coiled-coil domain containing 148	Zinc finger protein 821; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.472
CCDC181	CCDC148	ENSP00000356780	ENSP00000283233	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	Coiled-coil domain containing 148	0.751
CCDC181	LRRC49	ENSP00000356780	ENSP00000453273	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	0.725
CCDC181	PPP1R32	ENSP00000356780	ENSP00000344140	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	Protein phosphatase 1 regulatory subunit 32	0.472
CCDC181	SLC47A2	ENSP00000356780	ENSP00000326671	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	Multidrug and toxin extrusion protein 2; Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes	0.458
CDH26	CCDC148	ENSP00000339390	ENSP00000283233	Cadherin-like protein 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	Coiled-coil domain containing 148	0.581
CDH26	LRRC49	ENSP00000339390	ENSP00000453273	Cadherin-like protein 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	0.563
GALNT13	CCDC148	ENSP00000376570	ENSP00000283233	Polypeptide N-acetylgalactosaminyltransferase 13; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a much stronger activity than GALNT1 to transfer GalNAc to mucin peptides, such as Muc5Ac and Muc7. Able to glycosylate SDC3. May be responsible for the synthesis of Tn antigen in neuronal cells; Polypeptide N-acetylgalactosaminyltransferases	Coiled-coil domain containing 148	0.472
LRRC49	CCDC148	ENSP00000453273	ENSP00000283233	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	Coiled-coil domain containing 148	0.768
LRRC49	CCDC181	ENSP00000453273	ENSP00000356780	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	0.725
LRRC49	CDH26	ENSP00000453273	ENSP00000339390	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	Cadherin-like protein 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	0.563

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