node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOA | ZNF256 | ENSP00000378669 | ENSP00000282308 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.544 |
ASB8 | ZNF256 | ENSP00000320893 | ENSP00000282308 | Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Ankyrin repeat domain containing | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.490 |
DCAF4 | ZNF256 | ENSP00000351147 | ENSP00000282308 | DDB1- and CUL4-associated factor 4; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.445 |
DUS1L | RSPRY1 | ENSP00000346280 | ENSP00000443176 | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | Ring finger and SPRY domain containing 1 | 0.474 |
DUS1L | ZNF256 | ENSP00000346280 | ENSP00000282308 | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.434 |
RHOXF1 | ZNF256 | ENSP00000217999 | ENSP00000282308 | Rhox homeobox family member 1; Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis; PRD class homeoboxes and pseudogenes | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.461 |
RSPRY1 | DUS1L | ENSP00000443176 | ENSP00000346280 | Ring finger and SPRY domain containing 1 | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | 0.474 |
RSPRY1 | ZNF256 | ENSP00000443176 | ENSP00000282308 | Ring finger and SPRY domain containing 1 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.516 |
SDR42E1 | ZNF256 | ENSP00000332407 | ENSP00000282308 | Short chain dehydrogenase/reductase family 42E, member 1 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.455 |
TRIM28 | ZNF256 | ENSP00000253024 | ENSP00000282308 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.944 |
ZNF256 | ALDOA | ENSP00000282308 | ENSP00000378669 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | 0.544 |
ZNF256 | ASB8 | ENSP00000282308 | ENSP00000320893 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Ankyrin repeat domain containing | 0.490 |
ZNF256 | DCAF4 | ENSP00000282308 | ENSP00000351147 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | DDB1- and CUL4-associated factor 4; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | 0.445 |
ZNF256 | DUS1L | ENSP00000282308 | ENSP00000346280 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | 0.434 |
ZNF256 | RHOXF1 | ENSP00000282308 | ENSP00000217999 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | Rhox homeobox family member 1; Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis; PRD class homeoboxes and pseudogenes | 0.461 |
ZNF256 | RSPRY1 | ENSP00000282308 | ENSP00000443176 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | Ring finger and SPRY domain containing 1 | 0.516 |
ZNF256 | SDR42E1 | ENSP00000282308 | ENSP00000332407 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | Short chain dehydrogenase/reductase family 42E, member 1 | 0.455 |
ZNF256 | TRIM28 | ENSP00000282308 | ENSP00000253024 | Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.944 |