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  • 11.0 [archived version]
STRINGSTRING
DCAF4 DCAF4 ALDOA ALDOA RHOXF1 RHOXF1 TRIM28 TRIM28 ZNF256 ZNF256 ASB8 ASB8 SDR42E1 SDR42E1 RSPRY1 RSPRY1 DUS1L DUS1L
"ZNF256" - Zinc finger protein 256 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF256Zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity; Belongs to the krueppel C2H2-type zinc-finger protein family (627 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.944
ALDOA
Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family (418 aa)
           
  0.544
RSPRY1
Ring finger and SPRY domain containing 1 (576 aa)
       
 
  0.516
ASB8
Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Ankyrin repeat domain containing (288 aa)
     
 
  0.490
RHOXF1
Rhox homeobox family member 1; Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis; PRD class homeoboxes and pseudogenes (184 aa)
       
 
  0.461
SDR42E1
Short chain dehydrogenase/reductase family 42E, member 1 (393 aa)
       
 
  0.455
DCAF4
DDB1- and CUL4-associated factor 4; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors (495 aa)
           
  0.445
DUS1L
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (473 aa)
       
 
  0.434
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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