• Version:
  • 11.0 [archived version]
STRINGSTRING
RNF149 RNF149 COLQ COLQ PXMP4 PXMP4 SLC25A44 SLC25A44 DHFR DHFR GOLGA7 GOLGA7 MEF2BNB MEF2BNB FAM151B FAM151B ZFYVE16 ZFYVE16 NUDT22 NUDT22 ANKRD34B ANKRD34B
"FAM151B" - Protein FAM151B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM151BProtein FAM151B; Family with sequence similarity 151 member B (276 aa)    
Predicted Functional Partners:
ZFYVE16
Zinc finger FYVE domain-containing protein 16; May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes; Protein phosphatase 1 regulatory subunits (1539 aa)
 
       
  0.672
PXMP4
Peroxisomal membrane protein 4 (212 aa)
           
  0.617
ANKRD34B
Ankyrin repeat domain-containing protein 34B; Ankyrin repeat domain containing; Belongs to the ANKRD34 family (514 aa)
           
  0.616
NUDT22
Nucleoside diphosphate-linked moiety X motif 22; Nudix hydrolase family (303 aa)
           
  0.593
MEF2BNB
BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (119 aa)
           
  0.590
SLC25A44
Solute carrier family 25 member 44 (322 aa)
           
  0.577
GOLGA7
Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS (137 aa)
           
  0.577
DHFR
Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2 (187 aa)
           
  0.562
COLQ
Acetylcholinesterase collagenic tail peptide; Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina (455 aa)
           
  0.558
RNF149
E3 ubiquitin-protein ligase RNF149; E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation; Ring finger proteins (400 aa)
           
  0.541
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]