node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD34B | FAM151B | ENSP00000339802 | ENSP00000282226 | Ankyrin repeat domain-containing protein 34B; Ankyrin repeat domain containing; Belongs to the ANKRD34 family | Protein FAM151B; Family with sequence similarity 151 member B | 0.616 |
ANKRD34B | ZFYVE16 | ENSP00000339802 | ENSP00000337159 | Ankyrin repeat domain-containing protein 34B; Ankyrin repeat domain containing; Belongs to the ANKRD34 family | Zinc finger FYVE domain-containing protein 16; May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes; Protein phosphatase 1 regulatory subunits | 0.671 |
COLQ | FAM151B | ENSP00000373298 | ENSP00000282226 | Acetylcholinesterase collagenic tail peptide; Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina | Protein FAM151B; Family with sequence similarity 151 member B | 0.558 |
COLQ | PXMP4 | ENSP00000373298 | ENSP00000386385 | Acetylcholinesterase collagenic tail peptide; Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina | Peroxisomal membrane protein 4 | 0.454 |
COLQ | RNF149 | ENSP00000373298 | ENSP00000295317 | Acetylcholinesterase collagenic tail peptide; Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina | E3 ubiquitin-protein ligase RNF149; E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation; Ring finger proteins | 0.538 |
DHFR | FAM151B | ENSP00000396308 | ENSP00000282226 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2 | Protein FAM151B; Family with sequence similarity 151 member B | 0.562 |
FAM151B | ANKRD34B | ENSP00000282226 | ENSP00000339802 | Protein FAM151B; Family with sequence similarity 151 member B | Ankyrin repeat domain-containing protein 34B; Ankyrin repeat domain containing; Belongs to the ANKRD34 family | 0.616 |
FAM151B | COLQ | ENSP00000282226 | ENSP00000373298 | Protein FAM151B; Family with sequence similarity 151 member B | Acetylcholinesterase collagenic tail peptide; Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina | 0.558 |
FAM151B | DHFR | ENSP00000282226 | ENSP00000396308 | Protein FAM151B; Family with sequence similarity 151 member B | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2 | 0.562 |
FAM151B | GOLGA7 | ENSP00000282226 | ENSP00000350378 | Protein FAM151B; Family with sequence similarity 151 member B | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | 0.577 |
FAM151B | MEF2BNB | ENSP00000282226 | ENSP00000425864 | Protein FAM151B; Family with sequence similarity 151 member B | BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor | 0.590 |
FAM151B | NUDT22 | ENSP00000282226 | ENSP00000279206 | Protein FAM151B; Family with sequence similarity 151 member B | Nucleoside diphosphate-linked moiety X motif 22; Nudix hydrolase family | 0.593 |
FAM151B | PXMP4 | ENSP00000282226 | ENSP00000386385 | Protein FAM151B; Family with sequence similarity 151 member B | Peroxisomal membrane protein 4 | 0.617 |
FAM151B | RNF149 | ENSP00000282226 | ENSP00000295317 | Protein FAM151B; Family with sequence similarity 151 member B | E3 ubiquitin-protein ligase RNF149; E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation; Ring finger proteins | 0.541 |
FAM151B | SLC25A44 | ENSP00000282226 | ENSP00000407560 | Protein FAM151B; Family with sequence similarity 151 member B | Solute carrier family 25 member 44 | 0.577 |
FAM151B | ZFYVE16 | ENSP00000282226 | ENSP00000337159 | Protein FAM151B; Family with sequence similarity 151 member B | Zinc finger FYVE domain-containing protein 16; May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes; Protein phosphatase 1 regulatory subunits | 0.672 |
GOLGA7 | FAM151B | ENSP00000350378 | ENSP00000282226 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | Protein FAM151B; Family with sequence similarity 151 member B | 0.577 |
GOLGA7 | MEF2BNB | ENSP00000350378 | ENSP00000425864 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor | 0.549 |
GOLGA7 | PXMP4 | ENSP00000350378 | ENSP00000386385 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | Peroxisomal membrane protein 4 | 0.449 |
GOLGA7 | SLC25A44 | ENSP00000350378 | ENSP00000407560 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | Solute carrier family 25 member 44 | 0.556 |