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  • 11.0 [archived version]
STRINGSTRING
SLC35B3 SLC35B3 TCEANC TCEANC FAM179A FAM179A TRIM55 TRIM55 RNF219 RNF219 DNAJC5B DNAJC5B KIAA0355 KIAA0355 MTMR14 MTMR14 SETD5 SETD5 CEP85 CEP85 UBTF UBTF
"RNF219" - Ring finger protein 219 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF219Ring finger protein 219 (726 aa)    
Predicted Functional Partners:
FAM179A
TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A (1019 aa)
            
  0.774
SETD5
SET domain-containing protein 5; Probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Acts as a regulator of histone acetylation during gene transcription; SET domain containing (1442 aa)
            
  0.750
MTMR14
Myotubularin-related protein 14; Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3; Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily (650 aa)
            
  0.748
DNAJC5B
DnaJ heat shock protein family member C5 beta (199 aa)
            
  0.733
TCEANC
Transcription elongation factor A N-terminal and central domain containing (381 aa)
        
      0.723
SLC35B3
Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers (401 aa)
            
  0.667
TRIM55
Tripartite motif-containing protein 55; May regulate gene expression and protein turnover in muscle cells; Ring finger proteins (548 aa)
            
  0.588
UBTF
Nucleolar transcription factor 1; Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element (764 aa)
            
  0.574
KIAA0355
Uncharacterized protein KIAA0355; KIAA0355 (1070 aa)
            
  0.560
CEP85
Centrosomal protein of 85 kDa; Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity; Belongs to the CEP85 family (762 aa)
            
  0.555
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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