C4orf33 protein (human) - STRING database

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C4orf33

UPF0462 protein C4orf33; Chromosome 4 open reading frame 33 (199 aa)

Predicted Functional Partners:

UBE2K

0.823

TAF11

0.758

GPATCH11

0.702

SFT2D1

0.696

PHF11

0.685

CCDC185

0.631

CCDC109B

0.613

TMEM255A

0.607

ZFAND1

0.583

SAMD4A

0.546

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C4orf33	CCDC109B	ENSP00000281146	ENSP00000378145	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	Calcium uniporter regulatory subunit MCUb, mitochondrial; Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways	0.613
C4orf33	CCDC185	ENSP00000281146	ENSP00000355840	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	Coiled-coil domain containing 185	0.631
C4orf33	GPATCH11	ENSP00000281146	ENSP00000386772	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	G-patch domain containing 11	0.702
C4orf33	PHF11	ENSP00000281146	ENSP00000367570	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression; PHD finger proteins	0.685
C4orf33	SAMD4A	ENSP00000281146	ENSP00000375919	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	Protein Smaug homolog 1; Acts as a translational repressor of SRE-containing messengers; Belongs to the SMAUG family	0.546
C4orf33	SFT2D1	ENSP00000281146	ENSP00000354590	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex	0.696
C4orf33	TAF11	ENSP00000281146	ENSP00000354633	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	Transcription initiation factor TFIID subunit 11; Core TAFII present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively); Belongs to the TAF11 family	0.758
C4orf33	TMEM255A	ENSP00000281146	ENSP00000310110	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	Transmembrane protein 255A; Belongs to the TMEM255 family	0.607
C4orf33	UBE2K	ENSP00000281146	ENSP00000261427	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	Ubiquitin-conjugating enzyme E2 K; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of ’Lys-48’-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam [...]	0.823
C4orf33	ZFAND1	ENSP00000281146	ENSP00000220669	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	Zinc finger AN1-type containing 1	0.583
CCDC109B	C4orf33	ENSP00000378145	ENSP00000281146	Calcium uniporter regulatory subunit MCUb, mitochondrial; Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	0.613
CCDC109B	GPATCH11	ENSP00000378145	ENSP00000386772	Calcium uniporter regulatory subunit MCUb, mitochondrial; Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways	G-patch domain containing 11	0.564
CCDC109B	PHF11	ENSP00000378145	ENSP00000367570	Calcium uniporter regulatory subunit MCUb, mitochondrial; Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways	PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression; PHD finger proteins	0.524
CCDC109B	SAMD4A	ENSP00000378145	ENSP00000375919	Calcium uniporter regulatory subunit MCUb, mitochondrial; Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways	Protein Smaug homolog 1; Acts as a translational repressor of SRE-containing messengers; Belongs to the SMAUG family	0.416
CCDC109B	TMEM255A	ENSP00000378145	ENSP00000310110	Calcium uniporter regulatory subunit MCUb, mitochondrial; Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways	Transmembrane protein 255A; Belongs to the TMEM255 family	0.451
CCDC185	C4orf33	ENSP00000355840	ENSP00000281146	Coiled-coil domain containing 185	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	0.631
GPATCH11	C4orf33	ENSP00000386772	ENSP00000281146	G-patch domain containing 11	UPF0462 protein C4orf33; Chromosome 4 open reading frame 33	0.702
GPATCH11	CCDC109B	ENSP00000386772	ENSP00000378145	G-patch domain containing 11	Calcium uniporter regulatory subunit MCUb, mitochondrial; Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways	0.564
GPATCH11	PHF11	ENSP00000386772	ENSP00000367570	G-patch domain containing 11	PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression; PHD finger proteins	0.612
GPATCH11	SAMD4A	ENSP00000386772	ENSP00000375919	G-patch domain containing 11	Protein Smaug homolog 1; Acts as a translational repressor of SRE-containing messengers; Belongs to the SMAUG family	0.508

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