• Version:
  • 11.0 [archived version]
STRINGSTRING
LARP4B LARP4B WDR37 WDR37 IDI2 IDI2 CWH43 CWH43 ZMYND11 ZMYND11 DIP2C DIP2C KCNS2 KCNS2 NAGPA NAGPA ZCCHC14 ZCCHC14 AASDH AASDH STK32B STK32B
"DIP2C" - Disco interacting protein 2 homolog C in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2CDisco interacting protein 2 homolog C (1556 aa)    
Predicted Functional Partners:
STK32B
Serine/threonine kinase 32B (414 aa)
           
  0.727
LARP4B
La-related protein 4B; Stimulates mRNA translation; La ribonucleoprotein domain containing (738 aa)
           
  0.653
ZMYND11
Zinc finger MYND domain-containing protein 11; Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at ’Lys-36’ (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non- specifically to dsDNA. Acts as a tumor- suppressor by repressing a transcriptional program essential for tumor cell growth; Bromodomain containing (602 aa)
     
   
  0.652
CWH43
PGAP2-interacting protein; Involved in lipid remodeling during GPI-anchor maturation (699 aa)
           
  0.579
WDR37
WD repeat-containing protein 37; WD repeat domain containing (494 aa)
       
 
  0.574
KCNS2
Potassium voltage-gated channel subfamily S member 2; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2 (477 aa)
     
   
  0.565
ZCCHC14
Zinc finger CCHC domain-containing protein 14; Sterile alpha motif domain containing (949 aa)
     
   
  0.558
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P- mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N- acetylglucosaminyltransferases (515 aa)
           
  0.528
AASDH
Acyl-CoA synthetase family member 4; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA; Acyl-CoA synthetase family (1098 aa)
   
   
  0.516
IDI2
Isopentenyl-diphosphate delta-isomerase 2; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (227 aa)
           
  0.511
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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