node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIP | DCAKD | ENSP00000279146 | ENSP00000308515 | AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases | dephospho-CoA kinase domain containing | 0.547 |
AIP | PLBD2 | ENSP00000279146 | ENSP00000280800 | AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases | Putative phospholipase B-like 2; Putative phospholipase | 0.509 |
ALDH5A1 | KLHL8 | ENSP00000314649 | ENSP00000273963 | Succinate-semialdehyde dehydrogenase, mitochondrial; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA); Aldehyde dehydrogenases | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing | 0.465 |
ALDH5A1 | PLBD2 | ENSP00000314649 | ENSP00000280800 | Succinate-semialdehyde dehydrogenase, mitochondrial; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA); Aldehyde dehydrogenases | Putative phospholipase B-like 2; Putative phospholipase | 0.446 |
ALDH5A1 | RAB11FIP4 | ENSP00000314649 | ENSP00000482620 | Succinate-semialdehyde dehydrogenase, mitochondrial; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA); Aldehyde dehydrogenases | Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an ’address tag’ delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6; EF-hand domain containing | 0.425 |
DCAKD | AIP | ENSP00000308515 | ENSP00000279146 | dephospho-CoA kinase domain containing | AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases | 0.547 |
DCAKD | PLBD2 | ENSP00000308515 | ENSP00000280800 | dephospho-CoA kinase domain containing | Putative phospholipase B-like 2; Putative phospholipase | 0.628 |
EPB41L5 | KLHL8 | ENSP00000263713 | ENSP00000273963 | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells; FERM domain containing | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing | 0.539 |
EPB41L5 | PIP4K2C | ENSP00000263713 | ENSP00000347032 | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells; FERM domain containing | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum | 0.475 |
EPB41L5 | PLBD2 | ENSP00000263713 | ENSP00000280800 | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells; FERM domain containing | Putative phospholipase B-like 2; Putative phospholipase | 0.538 |
KLHL8 | ALDH5A1 | ENSP00000273963 | ENSP00000314649 | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing | Succinate-semialdehyde dehydrogenase, mitochondrial; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA); Aldehyde dehydrogenases | 0.465 |
KLHL8 | EPB41L5 | ENSP00000273963 | ENSP00000263713 | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells; FERM domain containing | 0.539 |
KLHL8 | PIP4K2C | ENSP00000273963 | ENSP00000347032 | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum | 0.554 |
KLHL8 | PLBD2 | ENSP00000273963 | ENSP00000280800 | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing | Putative phospholipase B-like 2; Putative phospholipase | 0.592 |
KLHL8 | RAB11FIP4 | ENSP00000273963 | ENSP00000482620 | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing | Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an ’address tag’ delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6; EF-hand domain containing | 0.585 |
PIP4K2C | EPB41L5 | ENSP00000347032 | ENSP00000263713 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells; FERM domain containing | 0.475 |
PIP4K2C | KLHL8 | ENSP00000347032 | ENSP00000273963 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing | 0.554 |
PIP4K2C | PLBD2 | ENSP00000347032 | ENSP00000280800 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum | Putative phospholipase B-like 2; Putative phospholipase | 0.537 |
PIP4K2C | RAB11FIP4 | ENSP00000347032 | ENSP00000482620 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum | Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an ’address tag’ delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6; EF-hand domain containing | 0.519 |
PLBD2 | AIP | ENSP00000280800 | ENSP00000279146 | Putative phospholipase B-like 2; Putative phospholipase | AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases | 0.509 |