node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMIGO1 | KCNA6 | ENSP00000358880 | ENSP00000280684 | Amphoterin-induced protein 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1; Belongs to the immunoglobulin superfamil [...] | Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; [...] | 0.538 |
DEPDC7 | KCNA6 | ENSP00000241051 | ENSP00000280684 | DEP domain containing 7; Belongs to the DEPDC7 family | Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; [...] | 0.529 |
ENSG00000270800 | FAU | ENSP00000475027 | ENSP00000435370 | RPS10-NUDT3 readthrough | Ubiquitin-like protein FUBI; FAU, ubiquitin like and ribosomal protein S30 fusion | 0.979 |
ENSG00000270800 | KCNA3 | ENSP00000475027 | ENSP00000358784 | RPS10-NUDT3 readthrough | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | 0.661 |
ENSG00000270800 | KCNA6 | ENSP00000475027 | ENSP00000280684 | RPS10-NUDT3 readthrough | Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; [...] | 0.661 |
ENSG00000270800 | RPL37A | ENSP00000475027 | ENSP00000418082 | RPS10-NUDT3 readthrough | Ribosomal protein L37a | 0.992 |
ENSG00000270800 | RPS28 | ENSP00000475027 | ENSP00000472469 | RPS10-NUDT3 readthrough | Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family | 0.995 |
FAU | ENSG00000270800 | ENSP00000435370 | ENSP00000475027 | Ubiquitin-like protein FUBI; FAU, ubiquitin like and ribosomal protein S30 fusion | RPS10-NUDT3 readthrough | 0.979 |
FAU | KCNA3 | ENSP00000435370 | ENSP00000358784 | Ubiquitin-like protein FUBI; FAU, ubiquitin like and ribosomal protein S30 fusion | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | 0.788 |
FAU | KCNA6 | ENSP00000435370 | ENSP00000280684 | Ubiquitin-like protein FUBI; FAU, ubiquitin like and ribosomal protein S30 fusion | Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; [...] | 0.788 |
FAU | RPL37A | ENSP00000435370 | ENSP00000418082 | Ubiquitin-like protein FUBI; FAU, ubiquitin like and ribosomal protein S30 fusion | Ribosomal protein L37a | 0.999 |
FAU | RPS28 | ENSP00000435370 | ENSP00000472469 | Ubiquitin-like protein FUBI; FAU, ubiquitin like and ribosomal protein S30 fusion | Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family | 0.999 |
KCNA3 | ENSG00000270800 | ENSP00000358784 | ENSP00000475027 | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | RPS10-NUDT3 readthrough | 0.661 |
KCNA3 | FAU | ENSP00000358784 | ENSP00000435370 | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | Ubiquitin-like protein FUBI; FAU, ubiquitin like and ribosomal protein S30 fusion | 0.788 |
KCNA3 | KCNA6 | ENSP00000358784 | ENSP00000280684 | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; [...] | 0.560 |
KCNA3 | KCNAB1 | ENSP00000358784 | ENSP00000419952 | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | Voltage-gated potassium channel subunit beta-1; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the clos [...] | 0.979 |
KCNA3 | KCNAB2 | ENSP00000358784 | ENSP00000367323 | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | Voltage-gated potassium channel subunit beta-2; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5 [...] | 0.980 |
KCNA3 | KCNAB3 | ENSP00000358784 | ENSP00000302719 | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | Voltage-gated potassium channel subunit beta-3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5; Aldo-keto reductases | 0.965 |
KCNA3 | RPL37A | ENSP00000358784 | ENSP00000418082 | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | Ribosomal protein L37a | 0.503 |
KCNA3 | RPS28 | ENSP00000358784 | ENSP00000472469 | Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient; Potassium voltage-gated channels | Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family | 0.493 |