node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD55 | CCDC138 | ENSP00000342295 | ENSP00000295124 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | Coiled-coil domain containing 138 | 0.718 |
ANKRD55 | CCDC61 | ENSP00000342295 | ENSP00000471454 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | Coiled-coil domain containing 61 | 0.445 |
ANKRD55 | KIAA1328 | ENSP00000342295 | ENSP00000280020 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | 0.723 |
ANKRD55 | PIBF1 | ENSP00000342295 | ENSP00000317144 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | Progesterone-induced-blocking factor 1; Isoform 1- Pericentriolar protein required to maintain mitotic spindle pole integrity. Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation. Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 | 0.436 |
ANKRD55 | SSX2IP | ENSP00000342295 | ENSP00000340279 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement- localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via a [...] | 0.416 |
ANKRD55 | TTLL5 | ENSP00000342295 | ENSP00000298832 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | Tubulin polyglutamylase TTLL5; Polyglutamylase which preferentially modifies alpha- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction; Tubulin tyrosine ligase family | 0.440 |
ANKRD55 | WDR90 | ENSP00000342295 | ENSP00000293879 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | WD repeat-containing protein 90; WD repeat domain containing | 0.744 |
C9orf129 | KIAA1328 | ENSP00000364568 | ENSP00000280020 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | 0.669 |
CCDC138 | ANKRD55 | ENSP00000295124 | ENSP00000342295 | Coiled-coil domain containing 138 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | 0.718 |
CCDC138 | CCDC61 | ENSP00000295124 | ENSP00000471454 | Coiled-coil domain containing 138 | Coiled-coil domain containing 61 | 0.774 |
CCDC138 | KIAA1328 | ENSP00000295124 | ENSP00000280020 | Coiled-coil domain containing 138 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | 0.744 |
CCDC138 | PIBF1 | ENSP00000295124 | ENSP00000317144 | Coiled-coil domain containing 138 | Progesterone-induced-blocking factor 1; Isoform 1- Pericentriolar protein required to maintain mitotic spindle pole integrity. Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation. Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 | 0.784 |
CCDC138 | SSX2IP | ENSP00000295124 | ENSP00000340279 | Coiled-coil domain containing 138 | Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement- localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via a [...] | 0.735 |
CCDC138 | TTLL5 | ENSP00000295124 | ENSP00000298832 | Coiled-coil domain containing 138 | Tubulin polyglutamylase TTLL5; Polyglutamylase which preferentially modifies alpha- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction; Tubulin tyrosine ligase family | 0.699 |
CCDC138 | WDR90 | ENSP00000295124 | ENSP00000293879 | Coiled-coil domain containing 138 | WD repeat-containing protein 90; WD repeat domain containing | 0.747 |
CCDC61 | ANKRD55 | ENSP00000471454 | ENSP00000342295 | Coiled-coil domain containing 61 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | 0.445 |
CCDC61 | CCDC138 | ENSP00000471454 | ENSP00000295124 | Coiled-coil domain containing 61 | Coiled-coil domain containing 138 | 0.774 |
CCDC61 | KIAA1328 | ENSP00000471454 | ENSP00000280020 | Coiled-coil domain containing 61 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | 0.766 |
CCDC61 | PIBF1 | ENSP00000471454 | ENSP00000317144 | Coiled-coil domain containing 61 | Progesterone-induced-blocking factor 1; Isoform 1- Pericentriolar protein required to maintain mitotic spindle pole integrity. Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation. Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 | 0.746 |
CCDC61 | SSX2IP | ENSP00000471454 | ENSP00000340279 | Coiled-coil domain containing 61 | Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement- localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via a [...] | 0.720 |