node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C10orf71 | KIAA1755 | ENSP00000363259 | ENSP00000279024 | Uncharacterized protein C10orf71; Chromosome 10 open reading frame 71 | Uncharacterized protein KIAA1755; KIAA1755 | 0.589 |
EML6 | EPB41L4A | ENSP00000348842 | ENSP00000261486 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | Erythrocyte membrane protein band 4.1 like 4A; FERM domain containing | 0.551 |
EML6 | ITM2C | ENSP00000348842 | ENSP00000322730 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF- induced cell death and neuronal differentiation (By similarity) | 0.576 |
EML6 | KIAA1755 | ENSP00000348842 | ENSP00000279024 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | Uncharacterized protein KIAA1755; KIAA1755 | 0.729 |
EML6 | SLC6A7 | ENSP00000348842 | ENSP00000230671 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | Sodium-dependent proline transporter; Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals; Solute carriers | 0.533 |
EPB41L4A | EML6 | ENSP00000261486 | ENSP00000348842 | Erythrocyte membrane protein band 4.1 like 4A; FERM domain containing | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | 0.551 |
EPB41L4A | ITM2C | ENSP00000261486 | ENSP00000322730 | Erythrocyte membrane protein band 4.1 like 4A; FERM domain containing | Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF- induced cell death and neuronal differentiation (By similarity) | 0.562 |
EPB41L4A | KIAA1755 | ENSP00000261486 | ENSP00000279024 | Erythrocyte membrane protein band 4.1 like 4A; FERM domain containing | Uncharacterized protein KIAA1755; KIAA1755 | 0.548 |
EPB41L4A | SLC6A7 | ENSP00000261486 | ENSP00000230671 | Erythrocyte membrane protein band 4.1 like 4A; FERM domain containing | Sodium-dependent proline transporter; Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals; Solute carriers | 0.432 |
ITM2C | EML6 | ENSP00000322730 | ENSP00000348842 | Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF- induced cell death and neuronal differentiation (By similarity) | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | 0.576 |
ITM2C | EPB41L4A | ENSP00000322730 | ENSP00000261486 | Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF- induced cell death and neuronal differentiation (By similarity) | Erythrocyte membrane protein band 4.1 like 4A; FERM domain containing | 0.562 |
ITM2C | KIAA1755 | ENSP00000322730 | ENSP00000279024 | Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF- induced cell death and neuronal differentiation (By similarity) | Uncharacterized protein KIAA1755; KIAA1755 | 0.680 |
ITM2C | SLC6A7 | ENSP00000322730 | ENSP00000230671 | Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF- induced cell death and neuronal differentiation (By similarity) | Sodium-dependent proline transporter; Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals; Solute carriers | 0.514 |
KIAA1755 | C10orf71 | ENSP00000279024 | ENSP00000363259 | Uncharacterized protein KIAA1755; KIAA1755 | Uncharacterized protein C10orf71; Chromosome 10 open reading frame 71 | 0.589 |
KIAA1755 | EML6 | ENSP00000279024 | ENSP00000348842 | Uncharacterized protein KIAA1755; KIAA1755 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | 0.729 |
KIAA1755 | EPB41L4A | ENSP00000279024 | ENSP00000261486 | Uncharacterized protein KIAA1755; KIAA1755 | Erythrocyte membrane protein band 4.1 like 4A; FERM domain containing | 0.548 |
KIAA1755 | ITM2C | ENSP00000279024 | ENSP00000322730 | Uncharacterized protein KIAA1755; KIAA1755 | Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF- induced cell death and neuronal differentiation (By similarity) | 0.680 |
KIAA1755 | OR51F1 | ENSP00000279024 | ENSP00000345163 | Uncharacterized protein KIAA1755; KIAA1755 | Olfactory receptor 51F1; Odorant receptor; Olfactory receptors, family 51 | 0.530 |
KIAA1755 | OR8G1 | ENSP00000279024 | ENSP00000476313 | Uncharacterized protein KIAA1755; KIAA1755 | Olfactory receptor 8G1; Odorant receptor; Olfactory receptors, family 8 | 0.589 |
KIAA1755 | OR8G5 | ENSP00000279024 | ENSP00000477014 | Uncharacterized protein KIAA1755; KIAA1755 | Olfactory receptor 8G5; Odorant receptor; Olfactory receptors, family 8 | 0.526 |