OOSP2 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OOSP2

Oocyte secreted protein 2 (158 aa)

Predicted Functional Partners:

MS4A3

0.761

TEX35

0.640

TEX37

0.628

ENDOU

0.614

BMP15

0.567

H1FOO

0.534

TRIM77

0.523

MPDU1

0.489

BANF2

0.478

ARHGAP20

0.478

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP20	OOSP2	ENSP00000260283	ENSP00000278855	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	Oocyte secreted protein 2	0.478
BANF2	OOSP2	ENSP00000439128	ENSP00000278855	Barrier-to-autointegration factor-like protein; May play a role in BANF1 regulation and influence tissue-specific roles of BANF1; Belongs to the BAF family	Oocyte secreted protein 2	0.478
BANF2	TEX35	ENSP00000439128	ENSP00000323795	Barrier-to-autointegration factor-like protein; May play a role in BANF1 regulation and influence tissue-specific roles of BANF1; Belongs to the BAF family	Testis-expressed protein 35; Testis expressed 35	0.427
BMP15	H1FOO	ENSP00000252677	ENSP00000319799	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth; Bone morphogenetic proteins	Histone H1oo; May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling ( [...]	0.770
BMP15	OOSP2	ENSP00000252677	ENSP00000278855	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth; Bone morphogenetic proteins	Oocyte secreted protein 2	0.567
BMP15	TRIM77	ENSP00000252677	ENSP00000474003	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth; Bone morphogenetic proteins	Tripartite motif containing 77; Belongs to the TRIM/RBCC family	0.472
ENDOU	OOSP2	ENSP00000397679	ENSP00000278855	Poly(U)-specific endoribonuclease; Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2’-3’-cyclic phosphate termini; Serine proteases	Oocyte secreted protein 2	0.614
H1FOO	BMP15	ENSP00000319799	ENSP00000252677	Histone H1oo; May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling ( [...]	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth; Bone morphogenetic proteins	0.770
H1FOO	OOSP2	ENSP00000319799	ENSP00000278855	Histone H1oo; May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling ( [...]	Oocyte secreted protein 2	0.534
H1FOO	TRIM77	ENSP00000319799	ENSP00000474003	Histone H1oo; May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling ( [...]	Tripartite motif containing 77; Belongs to the TRIM/RBCC family	0.523
MPDU1	OOSP2	ENSP00000250124	ENSP00000278855	Mannose-P-dolichol utilization defect 1 protein; Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors; Belongs to the MPDU1 (TC 2.A.43.3) family	Oocyte secreted protein 2	0.489
MS4A3	OOSP2	ENSP00000278865	ENSP00000278855	Membrane-spanning 4-domains subfamily A member 3; Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP); Belongs to the MS4A family	Oocyte secreted protein 2	0.761
OOSP2	ARHGAP20	ENSP00000278855	ENSP00000260283	Oocyte secreted protein 2	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	0.478
OOSP2	BANF2	ENSP00000278855	ENSP00000439128	Oocyte secreted protein 2	Barrier-to-autointegration factor-like protein; May play a role in BANF1 regulation and influence tissue-specific roles of BANF1; Belongs to the BAF family	0.478
OOSP2	BMP15	ENSP00000278855	ENSP00000252677	Oocyte secreted protein 2	Bone morphogenetic protein 15; May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth; Bone morphogenetic proteins	0.567
OOSP2	ENDOU	ENSP00000278855	ENSP00000397679	Oocyte secreted protein 2	Poly(U)-specific endoribonuclease; Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2’-3’-cyclic phosphate termini; Serine proteases	0.614
OOSP2	H1FOO	ENSP00000278855	ENSP00000319799	Oocyte secreted protein 2	Histone H1oo; May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling ( [...]	0.534
OOSP2	MPDU1	ENSP00000278855	ENSP00000250124	Oocyte secreted protein 2	Mannose-P-dolichol utilization defect 1 protein; Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors; Belongs to the MPDU1 (TC 2.A.43.3) family	0.489
OOSP2	MS4A3	ENSP00000278855	ENSP00000278865	Oocyte secreted protein 2	Membrane-spanning 4-domains subfamily A member 3; Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP); Belongs to the MS4A family	0.761
OOSP2	TEX35	ENSP00000278855	ENSP00000323795	Oocyte secreted protein 2	Testis-expressed protein 35; Testis expressed 35	0.640

page 1 of 2

Network

Fusion

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Neighborhood

© STRING Consortium 2020

Credits

Access

Info

About