• Version:
  • 11.0 [archived version]
STRINGSTRING
TRAF3IP3 TRAF3IP3 TMCC3 TMCC3 CXorf23 CXorf23 IFFO1 IFFO1 TMEM87A TMEM87A C11orf52 C11orf52 FRMD4A FRMD4A TMEM86A TMEM86A CRYGN CRYGN DTWD1 DTWD1 PPEF2 PPEF2
"C11orf52" - Uncharacterized protein C11orf52 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C11orf52Uncharacterized protein C11orf52; Chromosome 11 open reading frame 52 (123 aa)    
Predicted Functional Partners:
FRMD4A
FERM domain-containing protein 4A; Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling; FERM domain containing (1039 aa)
           
  0.581
TMEM86A
Lysoplasmalogenase-like protein TMEM86A; Transmembrane protein 86A (240 aa)
           
  0.512
IFFO1
Intermediate filament family orphan 1; Belongs to the intermediate filament family (571 aa)
           
  0.510
TMEM87A
Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) (555 aa)
           
  0.473
PPEF2
Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission; Belongs to the PPP phosphatase family (753 aa)
           
  0.450
DTWD1
DTW domain containing 1; Belongs to the DTW family (304 aa)
           
  0.449
CXorf23
BCLAF1 and THRAP3 family member 3; Chromosome X open reading frame 23; Belongs to the BCLAF1/THRAP3 family (682 aa)
           
  0.443
CRYGN
Beta-gamma crystallins (182 aa)
           
  0.430
TRAF3IP3
TRAF3-interacting JNK-activating modulator; May function as an adapter molecule that regulates TRAF3-mediated JNK activation (551 aa)
           
  0.420
TMCC3
Transmembrane and coiled-coil domain containing; Belongs to the TEX28 family (477 aa)
           
  0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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