• Version:
  • 11.0 [archived version]
STRINGSTRING
RPS11 RPS11 RPL6 RPL6 RPL3 RPL3 RPS4X RPS4X RPS14 RPS14 RPS5 RPS5 RPL8 RPL8 RPS16 RPS16 RPS2 RPS2 RPL4 RPL4 RPS3 RPS3
"RPS3" - 40S ribosomal protein S3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPS340S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein [...] (259 aa)    
Predicted Functional Partners:
RPS4X
Ribosomal protein S4, X-linked; Belongs to the eukaryotic ribosomal protein eS4 family (263 aa)
 
  0.999
RPS2
Ribosomal protein S2 (293 aa)
 
  0.999
RPS14
Ribosomal protein S14 (151 aa)
 
  0.999
RPL6
60S ribosomal protein L6; Component of the large ribosomal subunit (288 aa)
   
  0.999
RPS11
Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family (158 aa)
   
  0.999
RPL8
60S ribosomal protein L8; Component of the large ribosomal subunit (257 aa)
 
  0.999
RPS5
Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family (204 aa)
   
  0.999
RPS16
Ribosomal protein S16 (146 aa)
   
  0.999
RPL4
L ribosomal proteins (427 aa)
 
  0.999
RPL3
60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes; L ribosomal proteins (403 aa)
 
  0.999
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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