• Version:
  • 11.0 [archived version]
STRINGSTRING
GYS2 GYS2 APOL6 APOL6 TP53I11 TP53I11 ABHD1 ABHD1 KIRREL KIRREL GOLM1 GOLM1 ENDOD1 ENDOD1 PRR15L PRR15L PKP2 PKP2 LMAN2 LMAN2 C9orf152 C9orf152
"ENDOD1" - Endonuclease domain-containing 1 protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENDOD1Endonuclease domain-containing 1 protein; May act as a DNase and a RNase (500 aa)    
Predicted Functional Partners:
GOLM1
Golgi membrane protein 1; Unknown. Cellular response protein to viral infection; Belongs to the GOLM1/CASC4 family (401 aa)
           
  0.673
ABHD1
Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family (405 aa)
           
  0.658
C9orf152
Uncharacterized protein C9orf152; Chromosome 9 open reading frame 152 (239 aa)
           
  0.535
LMAN2
Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity) (356 aa)
           
  0.535
KIRREL
Kin of IRRE-like protein 1; Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity); Belongs to the immunoglobulin superfamily (757 aa)
           
  0.523
TP53I11
Tumor protein p53 inducible protein 11 (189 aa)
           
  0.522
PRR15L
Proline-rich protein 15-like protein; Proline rich 15 like; Belongs to the PRR15 family (103 aa)
           
  0.516
APOL6
Apolipoprotein L6; May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles; Apolipoproteins (343 aa)
           
  0.511
GYS2
Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Glycosyl transferases group 1 domain containing (703 aa)
           
  0.501
PKP2
Plakophilin-2; May play a role in junctional plaques; Armadillo repeat containing (881 aa)
           
  0.467
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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