| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDX10 | DHX33 | ENSP00000314348 | ENSP00000225296 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | 0.949 |
| DDX10 | EIF4A3 | ENSP00000314348 | ENSP00000269349 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all s [...] | 0.869 |
| DDX10 | MPHOSPH10 | ENSP00000314348 | ENSP00000244230 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; MPP10 subcomplex | 0.946 |
| DDX10 | NAT10 | ENSP00000314348 | ENSP00000257829 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1337 and 1842 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs (By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. Can acetylate both histones and microtubules. Histone acetyla [...] | 0.944 |
| DDX10 | NGDN | ENSP00000314348 | ENSP00000386134 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | Neuroguidin; Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs | 0.949 |
| DDX10 | NOM1 | ENSP00000314348 | ENSP00000275820 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus; Protein phosphatase 1 regulatory subunits | 0.952 |
| DDX10 | RBM19 | ENSP00000314348 | ENSP00000442053 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | Probable RNA-binding protein 19; Plays a role in embryo pre-implantation development; RNA binding motif containing | 0.900 |
| DDX10 | RRP9 | ENSP00000314348 | ENSP00000232888 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | U3 small nucleolar RNA-interacting protein 2; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA; Belongs to the WD repeat RRP9 family | 0.900 |
| DDX10 | WDR3 | ENSP00000314348 | ENSP00000308179 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | WD repeat-containing protein 3; WD repeat domain containing; Belongs to the WD repeat WDR3/UTP12 family | 0.898 |
| DHX33 | DDX10 | ENSP00000225296 | ENSP00000314348 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily | 0.949 |
| DHX33 | EIF4A2 | ENSP00000225296 | ENSP00000326381 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | Eukaryotic initiation factor 4A-II; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5’-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon; DEAD-box helicases | 0.516 |
| DHX33 | EIF4A3 | ENSP00000225296 | ENSP00000269349 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all s [...] | 0.933 |
| DHX33 | MPHOSPH10 | ENSP00000225296 | ENSP00000244230 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; MPP10 subcomplex | 0.837 |
| DHX33 | NAT10 | ENSP00000225296 | ENSP00000257829 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1337 and 1842 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs (By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. Can acetylate both histones and microtubules. Histone acetyla [...] | 0.928 |
| DHX33 | NGDN | ENSP00000225296 | ENSP00000386134 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | Neuroguidin; Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs | 0.895 |
| DHX33 | NOM1 | ENSP00000225296 | ENSP00000275820 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus; Protein phosphatase 1 regulatory subunits | 0.969 |
| DHX33 | RBM19 | ENSP00000225296 | ENSP00000442053 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | Probable RNA-binding protein 19; Plays a role in embryo pre-implantation development; RNA binding motif containing | 0.841 |
| DHX33 | RRP9 | ENSP00000225296 | ENSP00000232888 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | U3 small nucleolar RNA-interacting protein 2; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA; Belongs to the WD repeat RRP9 family | 0.952 |
| DHX33 | WDR3 | ENSP00000225296 | ENSP00000308179 | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | WD repeat-containing protein 3; WD repeat domain containing; Belongs to the WD repeat WDR3/UTP12 family | 0.846 |
| EIF4A2 | DHX33 | ENSP00000326381 | ENSP00000225296 | Eukaryotic initiation factor 4A-II; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5’-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon; DEAD-box helicases | Putative ATP-dependent RNA helicase DHX33; Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. Important element of nucleolar organization; DEAH-box helicases | 0.516 |
