• Version:
  • 11.0 [archived version]
STRINGSTRING
ZC3H12D ZC3H12D ZC3H12B ZC3H12B RC3H2 RC3H2 ZC3H7A ZC3H7A RBM26 RBM26 NUPL2 NUPL2 ZC3H4 ZC3H4 ZC3H15 ZC3H15 ZC3HAV1L ZC3HAV1L C7orf33 C7orf33 C7orf62 C7orf62
"ZC3HAV1L" - Zinc finger CCCH-type containing, antiviral 1 like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZC3HAV1LZinc finger CCCH-type containing, antiviral 1 like (300 aa)    
Predicted Functional Partners:
ZC3H15
Zinc finger CCCH domain-containing protein 15; Protects DRG1 from proteolytic degradation; Zinc fingers CCCH-type (426 aa)
           
  0.708
ZC3H12B
Probable ribonuclease ZC3H12B; May function as RNase and regulate the levels of target RNA species; Zinc fingers CCCH-type (836 aa)
           
  0.692
C7orf33
Uncharacterized protein C7orf33; Chromosome 7 open reading frame 33 (177 aa)
           
  0.658
ZC3H12D
Probable ribonuclease ZC3H12D; May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages. Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (527 aa)
           
  0.657
RBM26
RNA-binding protein 26; Protein phosphatase 1 regulatory subunits (1009 aa)
           
  0.640
ZC3H4
Zinc finger CCCH domain-containing protein 4; Armadillo-like helical domain containing (1303 aa)
           
  0.599
ZC3H7A
Zinc finger CCCH domain-containing protein 7A; May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 3’-ATA(A/T)-5’ motif in the apical loop; Tetratricopeptide repeat domain containing (971 aa)
           
  0.597
RC3H2
Roquin-2; Post-transcriptional repressor of mRNAs containing a conserved stem loop motif, called constitutive decay element (CDE), which is often located in the 3’-UTR, as in HMGXB3, ICOS, IER3, NFKBID, NFKBIZ, PPP1R10, TNF and in many more mRNAs. Binds to CDE and promotes mRNA deadenylation and degradation. This process does not involve miRNAs. In follicular helper T (Tfh) cells, represses of ICOS and TNFRSF4 expression, thus preventing spontaneous Tfh cell differentiation, germinal center B-cell differentiation in the absence of immunization and autoimmunity. In resting or LPS-stimul [...] (1191 aa)
     
   
  0.589
C7orf62
Testis-expressed protein 47; Chromosome 7 open reading frame 62 (253 aa)
           
  0.581
NUPL2
Nucleoporin-like protein 2; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope (423 aa)
           
  0.576
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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