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  • 11.0 [archived version]
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STAG3 STAG3 ABCB6 ABCB6 BMP5 BMP5 FAT3 FAT3 LDLRAD2 LDLRAD2 SSC4D SSC4D H1F0 H1F0 NUDCD1 NUDCD1 TMPRSS15 TMPRSS15 FBXO21 FBXO21 GCFC2 GCFC2
"SSC4D" - Scavenger receptor cysteine-rich domain-containing group B protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
SSC4DScavenger receptor cysteine-rich domain-containing group B protein; Scavenger receptor cysteine rich family member with 4 domains (575 aa)    
Predicted Functional Partners:
TMPRSS15
Enteropeptidase; Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases; Scavenger receptor cysteine rich domain containing (1019 aa)
           
  0.653
LDLRAD2
Low density lipoprotein receptor class A domain containing 2 (272 aa)
           
  0.585
FAT3
Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development; Cadherin related (4439 aa)
           
  0.572
FBXO21
F-box only protein 21; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other (628 aa)
           
  0.559
H1F0
Histone H1.0; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division (194 aa)
           
  0.538
BMP5
Bone morphogenetic protein 5; Induces cartilage and bone formation; Bone morphogenetic proteins (454 aa)
           
  0.487
NUDCD1
NudC domain containing 1 (583 aa)
           
  0.420
STAG3
Cohesin subunit SA-3; Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis- specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I; Armadillo-like helical domain containing (1226 aa)
           
  0.414
GCFC2
GC-rich sequence DNA-binding factor 2; Factor that represses transcription. It binds to the GC- rich sequences (5’-GCGGGGC-3’) present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons; Belongs to the GCF family (781 aa)
           
  0.411
ABCB6
ATP-binding cassette sub-family B member 6, mitochondrial; Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis; Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily (842 aa)
           
  0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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