MYLK4 protein (human) - STRING database

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MYLK4

Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family (388 aa)

Predicted Functional Partners:

MYL12A

0.835

MYL12B

0.834

MYL9

0.833

PRKCE

0.804

MCUR1

0.726

MYL3

0.723

OTOGL

0.711

STAMBPL1

0.708

MYLPF

0.706

MYL7

0.705

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCUR1	MYLK4	ENSP00000368468	ENSP00000274643	Mitochondrial calcium uniporter regulator 1; Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU. Probably involved in the assembly of the membrane components of the uniporter complex (uniplex); Belongs to the CCDC90 family	Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family	0.726
MCUR1	OTOGL	ENSP00000368468	ENSP00000400895	Mitochondrial calcium uniporter regulator 1; Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU. Probably involved in the assembly of the membrane components of the uniporter complex (uniplex); Belongs to the CCDC90 family	Otogelin-like protein; Otogelin like	0.666
MYL12A	MYL12B	ENSP00000217652	ENSP00000463559	Myosin regulatory light chain 12A; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity); EF-hand domain containing	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	0.966
MYL12A	MYL7	ENSP00000217652	ENSP00000223364	Myosin regulatory light chain 12A; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity); EF-hand domain containing	Myosin regulatory light chain 2, atrial isoform; EF-hand domain containing	0.901
MYL12A	MYL9	ENSP00000217652	ENSP00000279022	Myosin regulatory light chain 12A; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity); EF-hand domain containing	Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	0.923
MYL12A	MYLK4	ENSP00000217652	ENSP00000274643	Myosin regulatory light chain 12A; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity); EF-hand domain containing	Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family	0.835
MYL12A	MYLPF	ENSP00000217652	ENSP00000325239	Myosin regulatory light chain 12A; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity); EF-hand domain containing	Myosin light chain, phosphorylatable, fast skeletal muscle; EF-hand domain containing	0.901
MYL12B	MYL12A	ENSP00000463559	ENSP00000217652	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	Myosin regulatory light chain 12A; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity); EF-hand domain containing	0.966
MYL12B	MYL3	ENSP00000463559	ENSP00000379210	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing	0.427
MYL12B	MYL7	ENSP00000463559	ENSP00000223364	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	Myosin regulatory light chain 2, atrial isoform; EF-hand domain containing	0.901
MYL12B	MYL9	ENSP00000463559	ENSP00000279022	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	0.903
MYL12B	MYLK4	ENSP00000463559	ENSP00000274643	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family	0.834
MYL12B	MYLPF	ENSP00000463559	ENSP00000325239	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	Myosin light chain, phosphorylatable, fast skeletal muscle; EF-hand domain containing	0.900
MYL3	MYL12B	ENSP00000379210	ENSP00000463559	Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	0.427
MYL3	MYL7	ENSP00000379210	ENSP00000223364	Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing	Myosin regulatory light chain 2, atrial isoform; EF-hand domain containing	0.677
MYL3	MYL9	ENSP00000379210	ENSP00000279022	Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing	Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	0.774
MYL3	MYLK4	ENSP00000379210	ENSP00000274643	Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing	Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family	0.723
MYL3	MYLPF	ENSP00000379210	ENSP00000325239	Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing	Myosin light chain, phosphorylatable, fast skeletal muscle; EF-hand domain containing	0.786
MYL7	MYL12A	ENSP00000223364	ENSP00000217652	Myosin regulatory light chain 2, atrial isoform; EF-hand domain containing	Myosin regulatory light chain 12A; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity); EF-hand domain containing	0.901
MYL7	MYL12B	ENSP00000223364	ENSP00000463559	Myosin regulatory light chain 2, atrial isoform; EF-hand domain containing	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	0.901

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