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  • 11.0 [archived version]
STRINGSTRING
SLC10A7 SLC10A7 FRYL FRYL SLC35F2 SLC35F2 SLC38A9 SLC38A9 SLC18A3 SLC18A3 SLC10A4 SLC10A4 AQP10 AQP10 LPAR2 LPAR2 NKAIN1 NKAIN1 CLSTN2 CLSTN2 TMEM169 TMEM169
"SLC10A4" - Sodium/bile acid cotransporter 4 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
SLC10A4Sodium/bile acid cotransporter 4; Transporter for bile acids; Belongs to the bile acid-sodium symporter (BASS) (TC 2.A.28) family (437 aa)    
Predicted Functional Partners:
SLC10A7
Sodium/bile acid cotransporter 7; Solute carrier family 10 member 7; Belongs to the unknown BART superfamily-1 (UBS1) (TC 2.A.93) family (358 aa)
           
  0.801
SLC35F2
Solute carrier family 35 member F2; Putative solute transporter (374 aa)
     
 
  0.732
NKAIN1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 (207 aa)
     
   
  0.718
TMEM169
Transmembrane protein 169 (297 aa)
     
   
  0.711
FRYL
Protein furry homolog-like; Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (By similarity). May function as a transcriptional activator; Belongs to the furry protein family (3013 aa)
           
  0.667
SLC18A3
Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles; Solute carriers (532 aa)
     
   
  0.584
SLC38A9
Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino a [...] (561 aa)
   
 
  0.565
LPAR2
Lysophosphatidic acid receptor 2; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation (351 aa)
           
  0.547
AQP10
Aquaporin-10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol; Belongs to the MIP/aquaporin (TC 1.A.8) family (301 aa)
     
   
  0.515
CLSTN2
Calsyntenin-2; May modulate calcium-mediated postsynaptic signals; Cadherin related (955 aa)
     
   
  0.513
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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