GPR128 protein (human) - STRING database

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GPR128

Adhesion G-protein coupled receptor G7; Orphan receptor (797 aa)

Predicted Functional Partners:

GPR123

0.730

ARHGAP20

0.700

HNRNPM

0.655

TFG

0.556

ARMCX4

0.543

SORT1

0.529

PRPF40A

0.517

GUCA2B

0.499

PRSS35

0.488

SLC46A2

0.423

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP20	GPR128	ENSP00000260283	ENSP00000273352	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	Adhesion G-protein coupled receptor G7; Orphan receptor	0.700
ARHGAP20	HNRNPM	ENSP00000260283	ENSP00000325376	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	Heterogeneous nuclear ribonucleoprotein M; Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines	0.638
ARMCX4	GPR128	ENSP00000404304	ENSP00000273352	Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family	Adhesion G-protein coupled receptor G7; Orphan receptor	0.543
ARMCX4	GUCA2B	ENSP00000404304	ENSP00000361662	Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	0.540
ARMCX4	PRSS35	ENSP00000404304	ENSP00000358714	Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family	Serine protease 35	0.518
ARMCX4	SLC46A2	ENSP00000404304	ENSP00000363345	Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family	Thymic stromal cotransporter homolog; May act as a transporter; Belongs to the major facilitator superfamily. SLC46A family	0.519
GPR123	GPR128	ENSP00000376384	ENSP00000273352	Adhesion G protein-coupled receptor A1; Orphan receptor	Adhesion G-protein coupled receptor G7; Orphan receptor	0.730
GPR128	ARHGAP20	ENSP00000273352	ENSP00000260283	Adhesion G-protein coupled receptor G7; Orphan receptor	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	0.700
GPR128	ARMCX4	ENSP00000273352	ENSP00000404304	Adhesion G-protein coupled receptor G7; Orphan receptor	Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family	0.543
GPR128	GPR123	ENSP00000273352	ENSP00000376384	Adhesion G-protein coupled receptor G7; Orphan receptor	Adhesion G protein-coupled receptor A1; Orphan receptor	0.730
GPR128	GUCA2B	ENSP00000273352	ENSP00000361662	Adhesion G-protein coupled receptor G7; Orphan receptor	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	0.499
GPR128	HNRNPM	ENSP00000273352	ENSP00000325376	Adhesion G-protein coupled receptor G7; Orphan receptor	Heterogeneous nuclear ribonucleoprotein M; Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines	0.655
GPR128	PRPF40A	ENSP00000273352	ENSP00000386458	Adhesion G-protein coupled receptor G7; Orphan receptor	Pre-mRNA-processing factor 40 homolog A; Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing; Spliceosomal A complex	0.517
GPR128	PRSS35	ENSP00000273352	ENSP00000358714	Adhesion G-protein coupled receptor G7; Orphan receptor	Serine protease 35	0.488
GPR128	SLC46A2	ENSP00000273352	ENSP00000363345	Adhesion G-protein coupled receptor G7; Orphan receptor	Thymic stromal cotransporter homolog; May act as a transporter; Belongs to the major facilitator superfamily. SLC46A family	0.423
GPR128	SORT1	ENSP00000273352	ENSP00000256637	Adhesion G-protein coupled receptor G7; Orphan receptor	Sortilin; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differ [...]	0.529
GPR128	TFG	ENSP00000273352	ENSP00000240851	Adhesion G-protein coupled receptor G7; Orphan receptor	Protein TFG; Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules	0.556
GUCA2B	ARMCX4	ENSP00000361662	ENSP00000404304	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family	0.540
GUCA2B	GPR128	ENSP00000361662	ENSP00000273352	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	Adhesion G-protein coupled receptor G7; Orphan receptor	0.499
GUCA2B	PRSS35	ENSP00000361662	ENSP00000358714	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	Serine protease 35	0.486

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