node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1QL2 | FAM132A | ENSP00000272520 | ENSP00000329137 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue | 0.553 |
C1QL2 | FNDC5 | ENSP00000272520 | ENSP00000362570 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Fibronectin type III domain-containing protein 5; Irisin- Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue; Fibronectin type III domain containing | 0.586 |
C1QL2 | IBSP | ENSP00000272520 | ENSP00000226284 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment; SIBLING family | 0.508 |
C1QL2 | ICAM5 | ENSP00000272520 | ENSP00000221980 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Intercellular adhesion molecule 5; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2); Ig-like cell adhesion molecule family | 0.523 |
C1QL2 | ISLR2 | ENSP00000272520 | ENSP00000355402 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Immunoglobulin superfamily containing leucine-rich repeat protein 2; Required for axon extension during neural development; Immunoglobulin like domain containing | 0.476 |
C1QL2 | MXRA8 | ENSP00000272520 | ENSP00000399229 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Matrix remodeling-associated protein 8; May play a role in the maturation and maintenance of blood-brain barrier; V-set domain containing | 0.649 |
C1QL2 | NEUROD6 | ENSP00000272520 | ENSP00000297142 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Neurogenic differentiation factor 6; Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene (By similarity); Basic helix-loop-helix proteins | 0.490 |
C1QL2 | TFAP2D | ENSP00000272520 | ENSP00000008391 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Transcription factor AP-2-delta; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5’-GCCNNNGGC-3’ and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity) | 0.597 |
C1QL2 | YPEL1 | ENSP00000272520 | ENSP00000342832 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Yippee like family | 0.697 |
C1QL2 | YPEL4 | ENSP00000272520 | ENSP00000432648 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | Protein yippee-like 4; Yippee like family; Belongs to the yippee family | 0.736 |
FAM132A | C1QL2 | ENSP00000329137 | ENSP00000272520 | Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | 0.553 |
FNDC5 | C1QL2 | ENSP00000362570 | ENSP00000272520 | Fibronectin type III domain-containing protein 5; Irisin- Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue; Fibronectin type III domain containing | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | 0.586 |
FNDC5 | YPEL1 | ENSP00000362570 | ENSP00000342832 | Fibronectin type III domain-containing protein 5; Irisin- Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue; Fibronectin type III domain containing | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Yippee like family | 0.579 |
FNDC5 | YPEL4 | ENSP00000362570 | ENSP00000432648 | Fibronectin type III domain-containing protein 5; Irisin- Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue; Fibronectin type III domain containing | Protein yippee-like 4; Yippee like family; Belongs to the yippee family | 0.611 |
IBSP | C1QL2 | ENSP00000226284 | ENSP00000272520 | Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment; SIBLING family | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | 0.508 |
IBSP | ICAM5 | ENSP00000226284 | ENSP00000221980 | Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment; SIBLING family | Intercellular adhesion molecule 5; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2); Ig-like cell adhesion molecule family | 0.443 |
IBSP | MXRA8 | ENSP00000226284 | ENSP00000399229 | Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment; SIBLING family | Matrix remodeling-associated protein 8; May play a role in the maturation and maintenance of blood-brain barrier; V-set domain containing | 0.540 |
ICAM5 | C1QL2 | ENSP00000221980 | ENSP00000272520 | Intercellular adhesion molecule 5; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2); Ig-like cell adhesion molecule family | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity); C1q and TNF related | 0.523 |
ICAM5 | IBSP | ENSP00000221980 | ENSP00000226284 | Intercellular adhesion molecule 5; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2); Ig-like cell adhesion molecule family | Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment; SIBLING family | 0.443 |
ICAM5 | MXRA8 | ENSP00000221980 | ENSP00000399229 | Intercellular adhesion molecule 5; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2); Ig-like cell adhesion molecule family | Matrix remodeling-associated protein 8; May play a role in the maturation and maintenance of blood-brain barrier; V-set domain containing | 0.491 |