• Version:
  • 11.0 [archived version]
STRINGSTRING
PRAMEF2 PRAMEF2 DUX4 DUX4 DUX4L7 DUX4L7 DUX4L1 DUX4L1 DUX4L8 DUX4L8 MBD3L2 MBD3L2 KHDC1L KHDC1L ZSCAN4 ZSCAN4 TRIM43 TRIM43 PRAMEF12 PRAMEF12 CKM CKM
"TRIM43" - Tripartite motif containing 43 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM43Tripartite motif containing 43; Ring finger proteins (446 aa)    
Predicted Functional Partners:
MBD3L2
methyl-CpG binding domain protein 3 like 2; Belongs to the MBD3L family (208 aa)
     
   
  0.768
PRAMEF2
PRAME family member 2; Belongs to the PRAME family (474 aa)
     
   
  0.728
ZSCAN4
Zinc finger and SCAN domain-containing protein 4; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity); SCAN domain containing (433 aa)
     
 
  0.687
DUX4
Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family (424 aa)
       
 
  0.674
DUX4L1
Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes (424 aa)
       
 
  0.653
DUX4L7
Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes (424 aa)
       
 
  0.641
DUX4L8
Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes (424 aa)
       
 
  0.639
PRAMEF12
PRAME family member 12; Belongs to the PRAME family (483 aa)
     
   
  0.629
KHDC1L
Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family (128 aa)
     
   
  0.600
CKM
Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (381 aa)
           
  0.583
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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