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  • 11.0 [archived version]
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SEL1L3 SEL1L3 ERICH5 ERICH5 TMEM82 TMEM82 IMPA2 IMPA2 SLC44A3 SLC44A3 GDPD1 GDPD1 PCYT1B PCYT1B SLC39A2 SLC39A2 SLC5A7 SLC5A7 THADA THADA HUNK HUNK
"SLC44A3" - Choline transporter-like protein 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SLC44A3Choline transporter-like protein 3; Solute carrier family 44 member 3 (653 aa)    
Predicted Functional Partners:
GDPD1
Lysophospholipase D GDPD1; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC). May be involved in bioactive N-acylethanolamine biosynthesis. Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine (314 aa)
           
  0.549
IMPA2
Inositol monophosphatase 2; Can use myo-inositol monophosphates, scylloinositol 1,4- diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2’- AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+) action in brain (288 aa)
       
      0.548
SLC5A7
High affinity choline transporter 1; Transmembrane transporter that imports choline from the extracellular space into the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion-dependent; Belongs to the sodium-solute symporter (SSF) (TC 2.A.21) family (580 aa)
     
   
  0.504
ERICH5
Glutamate-rich protein 5; Glutamate rich 5 (374 aa)
     
   
  0.474
THADA
Thyroid adenoma-associated protein; THADA, armadillo repeat containing; Belongs to the THADA family (1953 aa)
           
  0.472
SEL1L3
Protein sel-1 homolog 3; SEL1L family member 3 (1132 aa)
     
   
  0.454
HUNK
Hormonally up-regulated Neu-associated kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily (714 aa)
     
   
  0.447
TMEM82
Transmembrane protein 82 (343 aa)
           
  0.441
PCYT1B
Choline-phosphate cytidylyltransferase B; Controls phosphatidylcholine synthesis (369 aa)
           
  0.437
SLC39A2
Zinc transporter ZIP2; Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis; Solute carriers (309 aa)
     
   
  0.428
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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