node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AURKAIP1 | EVA1B | ENSP00000342676 | ENSP00000270824 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | Eva-1 homolog B; Belongs to the EVA1 family | 0.530 |
AURKAIP1 | ZCCHC17 | ENSP00000342676 | ENSP00000480986 | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | Nucleolar protein of 40 kDa; Zinc finger CCHC-type containing 17 | 0.442 |
CINP | CKAP2L | ENSP00000216756 | ENSP00000305204 | Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling; Belongs to the CINP family | Cytoskeleton-associated protein 2-like; Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells | 0.405 |
CINP | EVA1B | ENSP00000216756 | ENSP00000270824 | Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling; Belongs to the CINP family | Eva-1 homolog B; Belongs to the EVA1 family | 0.556 |
CINP | IMMP1L | ENSP00000216756 | ENSP00000278200 | Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling; Belongs to the CINP family | Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | 0.520 |
CINP | ZZEF1 | ENSP00000216756 | ENSP00000371051 | Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling; Belongs to the CINP family | Zinc finger ZZ-type and EF-hand domain containing 1 | 0.530 |
CKAP2L | CINP | ENSP00000305204 | ENSP00000216756 | Cytoskeleton-associated protein 2-like; Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells | Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling; Belongs to the CINP family | 0.405 |
CKAP2L | EVA1B | ENSP00000305204 | ENSP00000270824 | Cytoskeleton-associated protein 2-like; Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells | Eva-1 homolog B; Belongs to the EVA1 family | 0.590 |
CKAP2L | IMMP1L | ENSP00000305204 | ENSP00000278200 | Cytoskeleton-associated protein 2-like; Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells | Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | 0.509 |
CKAP2L | ZZEF1 | ENSP00000305204 | ENSP00000371051 | Cytoskeleton-associated protein 2-like; Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells | Zinc finger ZZ-type and EF-hand domain containing 1 | 0.482 |
EVA1B | AURKAIP1 | ENSP00000270824 | ENSP00000342676 | Eva-1 homolog B; Belongs to the EVA1 family | Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation | 0.530 |
EVA1B | CINP | ENSP00000270824 | ENSP00000216756 | Eva-1 homolog B; Belongs to the EVA1 family | Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling; Belongs to the CINP family | 0.556 |
EVA1B | CKAP2L | ENSP00000270824 | ENSP00000305204 | Eva-1 homolog B; Belongs to the EVA1 family | Cytoskeleton-associated protein 2-like; Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells | 0.590 |
EVA1B | IMMP1L | ENSP00000270824 | ENSP00000278200 | Eva-1 homolog B; Belongs to the EVA1 family | Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | 0.690 |
EVA1B | OTUD3 | ENSP00000270824 | ENSP00000364261 | Eva-1 homolog B; Belongs to the EVA1 family | OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes ’Lys-6’- and ’Lys-11’-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains; OTU domain containing | 0.547 |
EVA1B | SH3D21 | ENSP00000270824 | ENSP00000421294 | Eva-1 homolog B; Belongs to the EVA1 family | SH3 domain containing 21 | 0.543 |
EVA1B | TBC1D10A | ENSP00000270824 | ENSP00000384996 | Eva-1 homolog B; Belongs to the EVA1 family | TBC1 domain family member 10A; Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A | 0.557 |
EVA1B | TBC1D2 | ENSP00000270824 | ENSP00000481721 | Eva-1 homolog B; Belongs to the EVA1 family | TBC1 domain family member 2A; Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion | 0.529 |
EVA1B | ZCCHC17 | ENSP00000270824 | ENSP00000480986 | Eva-1 homolog B; Belongs to the EVA1 family | Nucleolar protein of 40 kDa; Zinc finger CCHC-type containing 17 | 0.594 |
EVA1B | ZZEF1 | ENSP00000270824 | ENSP00000371051 | Eva-1 homolog B; Belongs to the EVA1 family | Zinc finger ZZ-type and EF-hand domain containing 1 | 0.665 |