• Version:
  • 11.0 [archived version]
STRINGSTRING
SH3D21 SH3D21 TBC1D2 TBC1D2 TBC1D10A TBC1D10A IMMP1L IMMP1L EVA1B EVA1B ZZEF1 ZZEF1 CINP CINP CKAP2L CKAP2L ZCCHC17 ZCCHC17 AURKAIP1 AURKAIP1 OTUD3 OTUD3
"EVA1B" - Eva-1 homolog B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVA1BEva-1 homolog B; Belongs to the EVA1 family (165 aa)    
Predicted Functional Partners:
IMMP1L
Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO (166 aa)
           
  0.690
ZZEF1
Zinc finger ZZ-type and EF-hand domain containing 1 (2961 aa)
           
  0.665
ZCCHC17
Nucleolar protein of 40 kDa; Zinc finger CCHC-type containing 17 (263 aa)
           
  0.594
CKAP2L
Cytoskeleton-associated protein 2-like; Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells (745 aa)
           
  0.590
TBC1D10A
TBC1 domain family member 10A; Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A (515 aa)
     
      0.557
CINP
Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling; Belongs to the CINP family (212 aa)
           
  0.556
OTUD3
OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes ’Lys-6’- and ’Lys-11’-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains; OTU domain containing (398 aa)
           
  0.547
SH3D21
SH3 domain containing 21 (645 aa)
     
   
  0.543
AURKAIP1
Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation (199 aa)
     
   
  0.530
TBC1D2
TBC1 domain family member 2A; Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion (928 aa)
     
   
  0.529
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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