node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GPR150 | GPR176 | ENSP00000369344 | ENSP00000453076 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | 0.949 |
GPR150 | GPR20 | ENSP00000369344 | ENSP00000366970 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | G-protein coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP; G protein-coupled receptors, Class A orphans | 0.949 |
GPR150 | GPR25 | ENSP00000369344 | ENSP00000301917 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | Probable G-protein coupled receptor 25; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.949 |
GPR150 | GPR27 | ENSP00000369344 | ENSP00000303149 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | Probable G-protein coupled receptor 27; Orphan receptor. Possible candidate for amine-like G- protein coupled receptor; G protein-coupled receptors, Class A orphans | 0.941 |
GPR150 | GPR32 | ENSP00000369344 | ENSP00000270590 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | Probable G-protein coupled receptor 32; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.926 |
GPR150 | GPR39 | ENSP00000369344 | ENSP00000327417 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity); G protein-coupled receptors, Class A orphans | 0.922 |
GPR150 | GPR45 | ENSP00000369344 | ENSP00000258456 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | Probable G-protein coupled receptor 45; Orphan receptor. May play a role in brain function; G protein-coupled receptors, Class A orphans | 0.938 |
GPR150 | GPR83 | ENSP00000369344 | ENSP00000243673 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | Probable G-protein coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor; G protein-coupled receptors, Class A orphans | 0.977 |
GPR150 | GPR84 | ENSP00000369344 | ENSP00000450310 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | G-protein coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10-0), undecanoic acid (C11-0) and lauric acid (C12-0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system | 0.923 |
GPR150 | SCTR | ENSP00000369344 | ENSP00000019103 | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | Secretin receptor; This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Glucagon receptor family | 0.908 |
GPR176 | GPR150 | ENSP00000453076 | ENSP00000369344 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | Probable G-protein coupled receptor 150; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.949 |
GPR176 | GPR20 | ENSP00000453076 | ENSP00000366970 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | G-protein coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP; G protein-coupled receptors, Class A orphans | 0.930 |
GPR176 | GPR25 | ENSP00000453076 | ENSP00000301917 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | Probable G-protein coupled receptor 25; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.945 |
GPR176 | GPR27 | ENSP00000453076 | ENSP00000303149 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | Probable G-protein coupled receptor 27; Orphan receptor. Possible candidate for amine-like G- protein coupled receptor; G protein-coupled receptors, Class A orphans | 0.939 |
GPR176 | GPR32 | ENSP00000453076 | ENSP00000270590 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | Probable G-protein coupled receptor 32; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.932 |
GPR176 | GPR39 | ENSP00000453076 | ENSP00000327417 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity); G protein-coupled receptors, Class A orphans | 0.922 |
GPR176 | GPR45 | ENSP00000453076 | ENSP00000258456 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | Probable G-protein coupled receptor 45; Orphan receptor. May play a role in brain function; G protein-coupled receptors, Class A orphans | 0.929 |
GPR176 | GPR83 | ENSP00000453076 | ENSP00000243673 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | Probable G-protein coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor; G protein-coupled receptors, Class A orphans | 0.911 |
GPR176 | GPR84 | ENSP00000453076 | ENSP00000450310 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | G-protein coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10-0), undecanoic acid (C11-0) and lauric acid (C12-0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system | 0.921 |
GPR176 | SCTR | ENSP00000453076 | ENSP00000019103 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | Secretin receptor; This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Glucagon receptor family | 0.901 |