node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMC6 | KLHDC4 | ENSP00000444156 | ENSP00000270583 | Armadillo repeat containing 6 | Kelch domain containing 4 | 0.728 |
ARMC7 | KLHDC4 | ENSP00000245543 | ENSP00000270583 | Armadillo repeat containing 7 | Kelch domain containing 4 | 0.603 |
ARMC7 | TMEM261 | ENSP00000245543 | ENSP00000350961 | Armadillo repeat containing 7 | Distal membrane-arm assembly complex protein 1; Required for the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I | 0.620 |
BMS1 | BOP1 | ENSP00000363642 | ENSP00000455106 | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | 0.994 |
BMS1 | BRIX1 | ENSP00000363642 | ENSP00000338862 | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | 0.930 |
BMS1 | KIAA0020 | ENSP00000363642 | ENSP00000380982 | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | 0.904 |
BMS1 | KLHDC4 | ENSP00000363642 | ENSP00000270583 | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | Kelch domain containing 4 | 0.652 |
BMS1 | MAK16 | ENSP00000363642 | ENSP00000353246 | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | Protein MAK16 homolog; RNA binding motif containing | 0.940 |
BMS1 | POLR1B | ENSP00000363642 | ENSP00000444136 | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | DNA-directed RNA polymerase I subunit RPA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity) | 0.893 |
BMS1 | SDAD1 | ENSP00000363642 | ENSP00000348596 | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family | 0.913 |
BOP1 | BMS1 | ENSP00000455106 | ENSP00000363642 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | 0.994 |
BOP1 | BRIX1 | ENSP00000455106 | ENSP00000338862 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | 0.990 |
BOP1 | KIAA0020 | ENSP00000455106 | ENSP00000380982 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | 0.916 |
BOP1 | KLHDC4 | ENSP00000455106 | ENSP00000270583 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | Kelch domain containing 4 | 0.734 |
BOP1 | MAK16 | ENSP00000455106 | ENSP00000353246 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | Protein MAK16 homolog; RNA binding motif containing | 0.985 |
BOP1 | POLR1B | ENSP00000455106 | ENSP00000444136 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | DNA-directed RNA polymerase I subunit RPA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity) | 0.905 |
BOP1 | SDAD1 | ENSP00000455106 | ENSP00000348596 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family | 0.906 |
BRIX1 | BMS1 | ENSP00000338862 | ENSP00000363642 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus | 0.930 |
BRIX1 | BOP1 | ENSP00000338862 | ENSP00000455106 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family | 0.990 |
BRIX1 | KIAA0020 | ENSP00000338862 | ENSP00000380982 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | 0.982 |