• Version:
  • 11.0 [archived version]
STRINGSTRING
SLC25A34 SLC25A34 NECAB1 NECAB1 PPAPDC1A PPAPDC1A FBLL1 FBLL1 OR4A5 OR4A5 ANKRD7 ANKRD7 CCDC24 CCDC24 ZFP14 ZFP14 PPP4R4 PPP4R4 TRIM28 TRIM28 OR4C12 OR4C12
"ZFP14" - Zinc finger protein 14 homolog in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
ZFP14Zinc finger protein 14 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type (533 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
ANKRD7
Ankyrin repeat domain-containing protein 7; Ankyrin repeat domain containing (254 aa)
     
 
  0.556
FBLL1
rRNA/tRNA 2’-O-methyltransferase fibrillarin-like protein 1; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2’-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Also acts as a protein methyltransferase by mediating methylation of glutamine residues (By similarity); Seven-beta-strand methyltransferase motif containing (334 aa)
           
  0.524
CCDC24
Coiled-coil domain containing 24 (307 aa)
           
  0.505
SLC25A34
Solute carrier family 25 member 34 (304 aa)
           
  0.496
OR4A5
Olfactory receptor 4A5; Odorant receptor; Olfactory receptors, family 4 (315 aa)
           
  0.491
PPAPDC1A
Phospholipid phosphatase 4; Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol; Belongs to the PA-phosphatase related phosphoesterase family (271 aa)
       
 
  0.486
NECAB1
N-terminal EF-hand calcium binding protein 1; EF-hand domain containing (351 aa)
           
  0.484
OR4C12
Olfactory receptor 4C12; Odorant receptor; Olfactory receptors, family 4 (309 aa)
           
  0.473
PPP4R4
Serine/threonine-protein phosphatase 4 regulatory subunit 4; Putative regulatory subunit of serine/threonine-protein phosphatase 4; Armadillo-like helical domain containing (873 aa)
           
  0.466
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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