| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP2A3 | CIB3 | ENSP00000353072 | ENSP00000269878 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction; ATPases Ca2+ transporting | Calcium and integrin binding family member 3; EF-hand domain containing | 0.687 |
| ATP2C1 | CIB3 | ENSP00000421326 | ENSP00000269878 | Calcium-transporting ATPase type 2C member 1; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily | Calcium and integrin binding family member 3; EF-hand domain containing | 0.682 |
| CIB3 | ATP2A3 | ENSP00000269878 | ENSP00000353072 | Calcium and integrin binding family member 3; EF-hand domain containing | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction; ATPases Ca2+ transporting | 0.687 |
| CIB3 | ATP2C1 | ENSP00000269878 | ENSP00000421326 | Calcium and integrin binding family member 3; EF-hand domain containing | Calcium-transporting ATPase type 2C member 1; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily | 0.682 |
| CIB3 | HSPB3 | ENSP00000269878 | ENSP00000303394 | Calcium and integrin binding family member 3; EF-hand domain containing | Heat shock protein beta-3; Inhibitor of actin polymerization; Small heat shock proteins | 0.637 |
| CIB3 | KIF11 | ENSP00000269878 | ENSP00000260731 | Calcium and integrin binding family member 3; EF-hand domain containing | Kinesin-like protein KIF11; Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily | 0.655 |
| CIB3 | KIF18A | ENSP00000269878 | ENSP00000263181 | Calcium and integrin binding family member 3; EF-hand domain containing | Kinesin-like protein KIF18A; Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression; Kinesins | 0.691 |
| CIB3 | KIF2C | ENSP00000269878 | ENSP00000361298 | Calcium and integrin binding family member 3; EF-hand domain containing | Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome- microtubule attachment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily | 0.691 |
| CIB3 | NR2C2AP | ENSP00000269878 | ENSP00000402756 | Calcium and integrin binding family member 3; EF-hand domain containing | Nuclear receptor 2C2-associated protein; May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes; Belongs to the NR2C2AP family | 0.607 |
| CIB3 | SLC25A42 | ENSP00000269878 | ENSP00000326693 | Calcium and integrin binding family member 3; EF-hand domain containing | Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate; Solute carriers | 0.677 |
| CIB3 | SLC35E1 | ENSP00000269878 | ENSP00000470652 | Calcium and integrin binding family member 3; EF-hand domain containing | Solute carrier family 35 member E1; Putative transporter; Solute carriers | 0.696 |
| CIB3 | TIMMDC1 | ENSP00000269878 | ENSP00000418803 | Calcium and integrin binding family member 3; EF-hand domain containing | Complex I assembly factor TIMMDC1, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I | 0.777 |
| HSPB3 | CIB3 | ENSP00000303394 | ENSP00000269878 | Heat shock protein beta-3; Inhibitor of actin polymerization; Small heat shock proteins | Calcium and integrin binding family member 3; EF-hand domain containing | 0.637 |
| KIF11 | CIB3 | ENSP00000260731 | ENSP00000269878 | Kinesin-like protein KIF11; Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily | Calcium and integrin binding family member 3; EF-hand domain containing | 0.655 |
| KIF11 | KIF18A | ENSP00000260731 | ENSP00000263181 | Kinesin-like protein KIF11; Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily | Kinesin-like protein KIF18A; Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression; Kinesins | 0.990 |
| KIF11 | KIF2C | ENSP00000260731 | ENSP00000361298 | Kinesin-like protein KIF11; Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily | Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome- microtubule attachment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily | 0.994 |
| KIF18A | CIB3 | ENSP00000263181 | ENSP00000269878 | Kinesin-like protein KIF18A; Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression; Kinesins | Calcium and integrin binding family member 3; EF-hand domain containing | 0.691 |
| KIF18A | KIF11 | ENSP00000263181 | ENSP00000260731 | Kinesin-like protein KIF18A; Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression; Kinesins | Kinesin-like protein KIF11; Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily | 0.990 |
| KIF18A | KIF2C | ENSP00000263181 | ENSP00000361298 | Kinesin-like protein KIF18A; Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression; Kinesins | Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome- microtubule attachment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily | 0.968 |
| KIF2C | CIB3 | ENSP00000361298 | ENSP00000269878 | Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome- microtubule attachment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily | Calcium and integrin binding family member 3; EF-hand domain containing | 0.691 |
