node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARL5C | ARL9 | ENSP00000269586 | ENSP00000353210 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | 0.716 |
ARL5C | CACNB2 | ENSP00000269586 | ENSP00000320025 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Voltage-dependent L-type calcium channel subunit beta-2; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting | 0.524 |
ARL5C | CUBN | ENSP00000269586 | ENSP00000367064 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Cubilin; Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. [...] | 0.523 |
ARL5C | ENSG00000182974 | ENSP00000269586 | ENSP00000329467 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Uncharacterized protein; Odorant receptor; Olfactory receptors, family 4 | 0.581 |
ARL5C | ENSG00000271786 | ENSP00000269586 | ENSP00000476221 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Uncharacterized protein | 0.529 |
ARL5C | ENSG00000274102 | ENSP00000269586 | ENSP00000483239 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Olfactory receptor 4M2; Odorant receptor; Olfactory receptors, family 4 | 0.582 |
ARL5C | NSUN6 | ENSP00000269586 | ENSP00000366519 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Putative methyltransferase NSUN6; May have S-adenosyl-L-methionine-dependent methyl- transferase activity; NOP2/Sun RNA methyltransferase family | 0.529 |
ARL5C | OR5D13 | ENSP00000269586 | ENSP00000354800 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Olfactory receptor 5D13; Odorant receptor; Olfactory receptors, family 5 | 0.670 |
ARL5C | SPEN | ENSP00000269586 | ENSP00000364912 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Msx2-interacting protein; May serve as a nuclear matrix platform that organizes and integrates transcriptional responses. In osteoblasts, supports transcription activation- synergizes with RUNX2 to enhance FGFR2- mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Has also been shown to be an essential corepressor protein, which probably regulates different key pathways such as the Notch pathway. Negative regulator of the Notch pathway via its interaction with RBPSUH, which prevents the association between NOTCH1 and RBPSUH, and therefore suppresses t [...] | 0.549 |
ARL5C | VWA5B1 | ENSP00000269586 | ENSP00000364220 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | Von Willebrand factor A domain containing 5B1 | 0.698 |
ARL9 | ARL5C | ENSP00000353210 | ENSP00000269586 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | 0.716 |
CACNB2 | ARL5C | ENSP00000320025 | ENSP00000269586 | Voltage-dependent L-type calcium channel subunit beta-2; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | 0.524 |
CACNB2 | CUBN | ENSP00000320025 | ENSP00000367064 | Voltage-dependent L-type calcium channel subunit beta-2; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting | Cubilin; Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. [...] | 0.462 |
CACNB2 | ENSG00000271786 | ENSP00000320025 | ENSP00000476221 | Voltage-dependent L-type calcium channel subunit beta-2; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting | Uncharacterized protein | 0.504 |
CACNB2 | NSUN6 | ENSP00000320025 | ENSP00000366519 | Voltage-dependent L-type calcium channel subunit beta-2; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting | Putative methyltransferase NSUN6; May have S-adenosyl-L-methionine-dependent methyl- transferase activity; NOP2/Sun RNA methyltransferase family | 0.567 |
CUBN | ARL5C | ENSP00000367064 | ENSP00000269586 | Cubilin; Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. [...] | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | 0.523 |
CUBN | CACNB2 | ENSP00000367064 | ENSP00000320025 | Cubilin; Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. [...] | Voltage-dependent L-type calcium channel subunit beta-2; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting | 0.462 |
CUBN | ENSG00000271786 | ENSP00000367064 | ENSP00000476221 | Cubilin; Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. [...] | Uncharacterized protein | 0.501 |
CUBN | NSUN6 | ENSP00000367064 | ENSP00000366519 | Cubilin; Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. [...] | Putative methyltransferase NSUN6; May have S-adenosyl-L-methionine-dependent methyl- transferase activity; NOP2/Sun RNA methyltransferase family | 0.555 |
ENSG00000182974 | ARL5C | ENSP00000329467 | ENSP00000269586 | Uncharacterized protein; Odorant receptor; Olfactory receptors, family 4 | Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP; ARF GTPase family | 0.581 |