node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C11orf57 | PHACTR2 | ENSP00000376767 | ENSP00000417038 | Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57 | Phosphatase and actin regulator 2 | 0.507 |
C11orf57 | USP38 | ENSP00000376767 | ENSP00000303434 | Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57 | Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards ’Lys-63’-linked ubiquitin chains; Belongs to the peptidase C19 family | 0.536 |
C11orf57 | ZCCHC2 | ENSP00000376767 | ENSP00000269499 | Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57 | Zinc finger CCHC-type containing 2 | 0.546 |
CMTR1 | ZCCHC2 | ENSP00000362550 | ENSP00000269499 | Cap-specific mRNA (nucleoside-2’-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2’-O-ribose methylation to the 5’-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway; G-patch domain containing | Zinc finger CCHC-type containing 2 | 0.682 |
DDX6 | GTPBP4 | ENSP00000478754 | ENSP00000354040 | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts; Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily | 0.427 |
DDX6 | ZCCHC2 | ENSP00000478754 | ENSP00000269499 | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts; Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily | Zinc finger CCHC-type containing 2 | 0.592 |
FBXO16 | ZCCHC2 | ENSP00000369604 | ENSP00000269499 | F-box only protein 16; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other | Zinc finger CCHC-type containing 2 | 0.556 |
GTPBP4 | DDX6 | ENSP00000354040 | ENSP00000478754 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts; Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily | 0.427 |
GTPBP4 | UTP15 | ENSP00000354040 | ENSP00000296792 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily | U3 small nucleolar RNA-associated protein 15 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre- ribosomal RNA transcription by RNA polymerase I; UTPa subcomplex | 0.951 |
GTPBP4 | ZCCHC2 | ENSP00000354040 | ENSP00000269499 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily | Zinc finger CCHC-type containing 2 | 0.552 |
KIAA1468 | ZCCHC2 | ENSP00000381198 | ENSP00000269499 | LisH domain and HEAT repeat-containing protein KIAA1468; Armadillo-like helical domain containing | Zinc finger CCHC-type containing 2 | 0.570 |
LYSMD2 | ZCCHC2 | ENSP00000267838 | ENSP00000269499 | LysM and putative peptidoglycan-binding domain-containing protein 2; LysM domain containing 2 | Zinc finger CCHC-type containing 2 | 0.582 |
PHACTR2 | C11orf57 | ENSP00000417038 | ENSP00000376767 | Phosphatase and actin regulator 2 | Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57 | 0.507 |
PHACTR2 | USP38 | ENSP00000417038 | ENSP00000303434 | Phosphatase and actin regulator 2 | Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards ’Lys-63’-linked ubiquitin chains; Belongs to the peptidase C19 family | 0.543 |
PHACTR2 | ZCCHC2 | ENSP00000417038 | ENSP00000269499 | Phosphatase and actin regulator 2 | Zinc finger CCHC-type containing 2 | 0.549 |
USP38 | C11orf57 | ENSP00000303434 | ENSP00000376767 | Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards ’Lys-63’-linked ubiquitin chains; Belongs to the peptidase C19 family | Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57 | 0.536 |
USP38 | PHACTR2 | ENSP00000303434 | ENSP00000417038 | Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards ’Lys-63’-linked ubiquitin chains; Belongs to the peptidase C19 family | Phosphatase and actin regulator 2 | 0.543 |
USP38 | ZCCHC2 | ENSP00000303434 | ENSP00000269499 | Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards ’Lys-63’-linked ubiquitin chains; Belongs to the peptidase C19 family | Zinc finger CCHC-type containing 2 | 0.555 |
UTP15 | GTPBP4 | ENSP00000296792 | ENSP00000354040 | U3 small nucleolar RNA-associated protein 15 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre- ribosomal RNA transcription by RNA polymerase I; UTPa subcomplex | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily | 0.951 |
UTP15 | ZCCHC2 | ENSP00000296792 | ENSP00000269499 | U3 small nucleolar RNA-associated protein 15 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre- ribosomal RNA transcription by RNA polymerase I; UTPa subcomplex | Zinc finger CCHC-type containing 2 | 0.582 |