| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIM2 | SECTM1 | ENSP00000357112 | ENSP00000269389 | Interferon-inducible protein AIM2; Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppr [...] | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.448 |
| ARL11 | SECTM1 | ENSP00000282026 | ENSP00000269389 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.514 |
| CD7 | SECTM1 | ENSP00000312027 | ENSP00000269389 | T-cell antigen CD7; Not yet known; CD molecules | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.963 |
| IFI6 | SECTM1 | ENSP00000342513 | ENSP00000269389 | Interferon alpha inducible protein 6 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.470 |
| IFNG | SECTM1 | ENSP00000229135 | ENSP00000269389 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.516 |
| KRT12 | SECTM1 | ENSP00000251643 | ENSP00000269389 | Keratin, type I cytoskeletal 12; May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity); Keratins, type I | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.512 |
| SECTM1 | AIM2 | ENSP00000269389 | ENSP00000357112 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | Interferon-inducible protein AIM2; Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppr [...] | 0.448 |
| SECTM1 | ARL11 | ENSP00000269389 | ENSP00000282026 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor; Belongs to the small GTPase superfamily. Arf family | 0.514 |
| SECTM1 | CD7 | ENSP00000269389 | ENSP00000312027 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | T-cell antigen CD7; Not yet known; CD molecules | 0.963 |
| SECTM1 | IFI6 | ENSP00000269389 | ENSP00000342513 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | Interferon alpha inducible protein 6 | 0.470 |
| SECTM1 | IFNG | ENSP00000269389 | ENSP00000229135 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family | 0.516 |
| SECTM1 | KRT12 | ENSP00000269389 | ENSP00000251643 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | Keratin, type I cytoskeletal 12; May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity); Keratins, type I | 0.512 |
| SECTM1 | TEX19 | ENSP00000269389 | ENSP00000331500 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | Testis-expressed protein 19; Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and prevent their mobilization. Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence element [...] | 0.656 |
| SECTM1 | TMIGD1 | ENSP00000269389 | ENSP00000332404 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | Transmembrane and immunoglobulin domain-containing protein 1; May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival; I-set domain containing | 0.441 |
| SECTM1 | UTS2R | ENSP00000269389 | ENSP00000323516 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | Urotensin-2 receptor; High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system | 0.658 |
| SECTM1 | ZMYND15 | ENSP00000269389 | ENSP00000269289 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | Zinc finger MYND domain-containing protein 15; Acts as a transcriptional repressor through interaction with histone deacetylases (HDACs). May be important for spermiogenesis; Zinc fingers MYND-type | 0.508 |
| TEX19 | SECTM1 | ENSP00000331500 | ENSP00000269389 | Testis-expressed protein 19; Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and prevent their mobilization. Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence element [...] | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.656 |
| TEX19 | UTS2R | ENSP00000331500 | ENSP00000323516 | Testis-expressed protein 19; Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and prevent their mobilization. Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence element [...] | Urotensin-2 receptor; High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system | 0.634 |
| TMIGD1 | SECTM1 | ENSP00000332404 | ENSP00000269389 | Transmembrane and immunoglobulin domain-containing protein 1; May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival; I-set domain containing | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.441 |
| UTS2R | SECTM1 | ENSP00000323516 | ENSP00000269389 | Urotensin-2 receptor; High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system | Secreted and transmembrane protein 1; May be involved in thymocyte signaling | 0.658 |
