node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C12orf4 | C18orf8 | ENSP00000261250 | ENSP00000269221 | Protein C12orf4; Plays a role in mast cell degranulation | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | 0.608 |
C18orf8 | C12orf4 | ENSP00000269221 | ENSP00000261250 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | Protein C12orf4; Plays a role in mast cell degranulation | 0.608 |
C18orf8 | CCZ1 | ENSP00000269221 | ENSP00000325681 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | CCZ1 homolog, vacuolar protein trafficking and biogenesis associated | 0.936 |
C18orf8 | LAMC1 | ENSP00000269221 | ENSP00000258341 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | 0.720 |
C18orf8 | MAGEH1 | ENSP00000269221 | ENSP00000343706 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | Melanoma-associated antigen H1; MAGE family member H1 | 0.573 |
C18orf8 | MON1A | ENSP00000269221 | ENSP00000296473 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | Vacuolar fusion protein MON1 homolog A; Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form | 0.902 |
C18orf8 | MON1B | ENSP00000269221 | ENSP00000248248 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | MON1 homolog B, secretory trafficking associated; Belongs to the MON1/SAND family | 0.911 |
C18orf8 | PTCHD2 | ENSP00000269221 | ENSP00000294484 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | Protein dispatched homolog 3; Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol (By similarity). Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells (By similarity) | 0.557 |
C18orf8 | SLC20A2 | ENSP00000269221 | ENSP00000340465 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | Sodium-dependent phosphate transporter 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retrov [...] | 0.800 |
C18orf8 | XPR1 | ENSP00000269221 | ENSP00000356562 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | Xenotropic and polytropic retrovirus receptor 1; Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5- InsP7); these are important intracellular signaling molecules; Solute carriers | 0.908 |
C18orf8 | YARS2 | ENSP00000269221 | ENSP00000320658 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | Tyrosine--tRNA ligase, mitochondrial; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family | 0.551 |
CCZ1 | C18orf8 | ENSP00000325681 | ENSP00000269221 | CCZ1 homolog, vacuolar protein trafficking and biogenesis associated | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | 0.936 |
CCZ1 | MON1A | ENSP00000325681 | ENSP00000296473 | CCZ1 homolog, vacuolar protein trafficking and biogenesis associated | Vacuolar fusion protein MON1 homolog A; Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form | 0.996 |
CCZ1 | MON1B | ENSP00000325681 | ENSP00000248248 | CCZ1 homolog, vacuolar protein trafficking and biogenesis associated | MON1 homolog B, secretory trafficking associated; Belongs to the MON1/SAND family | 0.995 |
LAMC1 | C18orf8 | ENSP00000258341 | ENSP00000269221 | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | 0.720 |
LAMC1 | SLC20A2 | ENSP00000258341 | ENSP00000340465 | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | Sodium-dependent phosphate transporter 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retrov [...] | 0.549 |
LAMC1 | XPR1 | ENSP00000258341 | ENSP00000356562 | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | Xenotropic and polytropic retrovirus receptor 1; Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5- InsP7); these are important intracellular signaling molecules; Solute carriers | 0.748 |
MAGEH1 | C18orf8 | ENSP00000343706 | ENSP00000269221 | Melanoma-associated antigen H1; MAGE family member H1 | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | 0.573 |
MON1A | C18orf8 | ENSP00000296473 | ENSP00000269221 | Vacuolar fusion protein MON1 homolog A; Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form | Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family | 0.902 |
MON1A | CCZ1 | ENSP00000296473 | ENSP00000325681 | Vacuolar fusion protein MON1 homolog A; Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form | CCZ1 homolog, vacuolar protein trafficking and biogenesis associated | 0.996 |