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  • 11.0 [archived version]
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LAMC1 LAMC1 XPR1 XPR1 MAGEH1 MAGEH1 SLC20A2 SLC20A2 C18orf8 C18orf8 CCZ1 CCZ1 YARS2 YARS2 MON1B MON1B MON1A MON1A C12orf4 C12orf4 PTCHD2 PTCHD2
"C18orf8" - Uncharacterized protein C18orf8 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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C18orf8Uncharacterized protein C18orf8; Chromosome 18 open reading frame 8; Belongs to the Mic1 family (657 aa)    
Predicted Functional Partners:
CCZ1
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated (482 aa)
     
 
  0.936
MON1B
MON1 homolog B, secretory trafficking associated; Belongs to the MON1/SAND family (547 aa)
     
 
    0.911
XPR1
Xenotropic and polytropic retrovirus receptor 1; Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5- InsP7); these are important intracellular signaling molecules; Solute carriers (696 aa)
           
  0.908
MON1A
Vacuolar fusion protein MON1 homolog A; Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (652 aa)
     
 
    0.902
SLC20A2
Sodium-dependent phosphate transporter 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retrov [...] (652 aa)
           
  0.800
LAMC1
Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (1609 aa)
           
  0.720
C12orf4
Protein C12orf4; Plays a role in mast cell degranulation (552 aa)
     
   
  0.608
MAGEH1
Melanoma-associated antigen H1; MAGE family member H1 (219 aa)
           
  0.573
PTCHD2
Protein dispatched homolog 3; Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol (By similarity). Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells (By similarity) (1392 aa)
           
  0.557
YARS2
Tyrosine--tRNA ligase, mitochondrial; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family (477 aa)
 
 
        0.551
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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