• Version:
  • 11.0 [archived version]
STRINGSTRING
OR7G3 OR7G3 SLC22A24 SLC22A24 FAM187B FAM187B DEFB133 DEFB133 WDR89 WDR89 ABCA10 ABCA10 MAP2K6 MAP2K6 ABCC9 ABCC9 ABCF3 ABCF3 VSIG10L VSIG10L ABCC11 ABCC11
"ABCA10" - ATP-binding cassette sub-family A member 10 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABCA10ATP-binding cassette sub-family A member 10; Probable transporter which may play a role in macrophage lipid homeostasis; ATP binding cassette subfamily A (1543 aa)    
Predicted Functional Partners:
ABCF3
ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F (709 aa)
     
 
  0.590
ABCC9
ATP-binding cassette sub-family C member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily (1549 aa)
     
 
  0.558
MAP2K6
Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 i [...] (334 aa)
           
  0.540
DEFB133
Beta-defensin 133; Has antibacterial activity; Defensins, beta (61 aa)
           
  0.511
VSIG10L
V-set and immunoglobulin domain containing 10 like (867 aa)
           
  0.510
ABCC11
ATP-binding cassette sub-family C member 11; Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S- conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D- glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taur [...] (1382 aa)
     
 
  0.495
SLC22A24
Solute carrier family 22 member 24 (552 aa)
     
 
  0.494
FAM187B
Protein FAM187B; Family with sequence similarity 187 member B (369 aa)
           
  0.477
WDR89
WD repeat-containing protein 89; WD repeat domain containing (387 aa)
           
  0.471
OR7G3
Olfactory receptor 7G3; Odorant receptor; Olfactory receptors, family 7 (312 aa)
           
  0.463
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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