GFOD2 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GFOD2

Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly (385 aa)

Predicted Functional Partners:

NKIRAS2

0.869

UROC1

0.738

GFOD1

0.684

LRRC29

0.622

TBCCD1

0.613

DNAJB7

0.549

SPRYD7

0.543

TSNAXIP1

0.543

B4GALNT1

0.541

DUS2

0.540

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B4GALNT1	GFOD2	ENSP00000341562	ENSP00000268797	Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2; Beta 4-glycosyltransferases	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	0.541
DNAJB7	GFOD2	ENSP00000307197	ENSP00000268797	DnaJ homolog subfamily B member 7; Probably acts as a co-chaperone; DNAJ heat shock proteins	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	0.549
DNAJB7	TBCCD1	ENSP00000307197	ENSP00000411253	DnaJ homolog subfamily B member 7; Probably acts as a co-chaperone; DNAJ heat shock proteins	TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration	0.549
DUS2	GFOD2	ENSP00000455229	ENSP00000268797	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	0.540
DUS2	LRRC29	ENSP00000455229	ENSP00000387318	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR	Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation	0.562
DUS2	SPRYD7	ENSP00000455229	ENSP00000354774	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR	SPRY domain containing 7	0.446
GFOD1	GFOD2	ENSP00000368589	ENSP00000268797	Glucose-fructose oxidoreductase domain containing 1	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	0.684
GFOD1	NKIRAS2	ENSP00000368589	ENSP00000303580	Glucose-fructose oxidoreductase domain containing 1	NF-kappa-B inhibitor-interacting Ras-like protein 2; Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF- kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity); Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily	0.828
GFOD2	B4GALNT1	ENSP00000268797	ENSP00000341562	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2; Beta 4-glycosyltransferases	0.541
GFOD2	DNAJB7	ENSP00000268797	ENSP00000307197	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	DnaJ homolog subfamily B member 7; Probably acts as a co-chaperone; DNAJ heat shock proteins	0.549
GFOD2	DUS2	ENSP00000268797	ENSP00000455229	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR	0.540
GFOD2	GFOD1	ENSP00000268797	ENSP00000368589	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	Glucose-fructose oxidoreductase domain containing 1	0.684
GFOD2	LRRC29	ENSP00000268797	ENSP00000387318	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation	0.622
GFOD2	NKIRAS2	ENSP00000268797	ENSP00000303580	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	NF-kappa-B inhibitor-interacting Ras-like protein 2; Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF- kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity); Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily	0.869
GFOD2	SPRYD7	ENSP00000268797	ENSP00000354774	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	SPRY domain containing 7	0.543
GFOD2	TBCCD1	ENSP00000268797	ENSP00000411253	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration	0.613
GFOD2	TSNAXIP1	ENSP00000268797	ENSP00000457241	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis	0.543
GFOD2	UROC1	ENSP00000268797	ENSP00000373073	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	Urocanate hydratase 1	0.738
LRRC29	DUS2	ENSP00000387318	ENSP00000455229	Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR	0.562
LRRC29	GFOD2	ENSP00000387318	ENSP00000268797	Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation	Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly	0.622

page 1 of 2

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About