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  • 11.0 [archived version]
STRINGSTRING
HRG HRG APOM APOM CCNJL CCNJL CDA CDA ADAD2 ADAD2 ATRN ATRN NICN1 NICN1 C14orf159 C14orf159 CLRN3 CLRN3 HSDL1 HSDL1 SLC38A8 SLC38A8
"ADAD2" - Adenosine deaminase domain containing 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADAD2Adenosine deaminase domain containing 2; Adenosine deaminases acting on RNA (665 aa)    
Predicted Functional Partners:
CCNJL
Cyclin-J-like protein; Cyclin J like; Cyclins (435 aa)
           
  0.554
C14orf159
D-glutamate cyclase, mitochondrial; D-glutamate cyclase that converts D-glutamate to 5-oxo- D-proline (621 aa)
           
  0.489
ATRN
Attractin; Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity); C-type lectin domain containing (1429 aa)
           
  0.482
HRG
Histidine-rich glycoprotein; Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Binds heparin and heparin/glycosaminoglycans in a zinc-dependent manner. Binds heparan sulfate on the surface of liver, lung, kidney and heart endothelial cells. Binds to N-sulfated polysaccharide chains on the surface of liver endothelial cells. Inhibits rosette formation. Acts as an adapter protein and is implicated in regulating many processes such as immune complex and pathogen clearance, cell chemotaxis, cell [...] (525 aa)
           
  0.478
APOM
Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid; Apolipoproteins (188 aa)
           
  0.477
HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1; Short chain dehydrogenase/reductase superfamily; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily (330 aa)
     
   
  0.476
CLRN3
Clarin-3; Clarin 3; Belongs to the clarin family (226 aa)
           
  0.470
NICN1
Nicolin-1; Nicolin 1 (213 aa)
           
  0.460
CDA
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis (146 aa)
           
  0.453
SLC38A8
Putative sodium-coupled neutral amino acid transporter 8; Putative sodium-dependent amino acid/proton antiporter; Belongs to the amino acid/polyamine transporter 2 family (435 aa)
           
  0.442
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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