• Version:
  • 11.0 [archived version]
STRINGSTRING
S100A12 S100A12 C10orf82 C10orf82 CMTM3 CMTM3 C11orf71 C11orf71 CMTM2 CMTM2 CMTM7 CMTM7 CKLF CKLF CMTM8 CMTM8 CMTM4 CMTM4 CMTM6 CMTM6 CMTM5 CMTM5
"CMTM2" - CKLF like MARVEL transmembrane domain containing 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
CMTM2CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family (248 aa)    
Predicted Functional Partners:
CKLF
Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 (152 aa)
     
   
  0.905
CMTM3
CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family (182 aa)
           
  0.905
CMTM4
CKLF like MARVEL transmembrane domain containing 4 (234 aa)
           
  0.905
CMTM7
CKLF like MARVEL transmembrane domain containing 7; Belongs to the chemokine-like factor family (175 aa)
           
  0.800
CMTM6
CKLF like MARVEL transmembrane domain containing 6; Belongs to the chemokine-like factor family (183 aa)
           
  0.723
CMTM5
CKLF like MARVEL transmembrane domain containing 5; Belongs to the chemokine-like factor family (223 aa)
     
   
  0.558
CMTM8
CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family (173 aa)
           
  0.511
S100A12
Protein S100-A12; S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leadin [...] (92 aa)
     
        0.478
C10orf82
Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82 (154 aa)
     
   
  0.459
C11orf71
Uncharacterized protein C11orf71; Chromosome 11 open reading frame 71 (147 aa)
           
  0.451
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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