• Version:
  • 11.0 [archived version]
STRINGSTRING
TSGA10IP TSGA10IP OR8G1 OR8G1 WDR70 WDR70 NPIPB8 NPIPB8 SMC5 SMC5 ZNF280D ZNF280D PAIP2B PAIP2B FAM195A FAM195A FAM214A FAM214A NOP9 NOP9 FAM227B FAM227B
"ZNF280D" - Zinc finger protein 280D in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF280DZinc finger protein 280D; May function as a transcription factor (979 aa)    
Predicted Functional Partners:
FAM195A
MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A (160 aa)
           
  0.712
FAM227B
Protein FAM227B; Family with sequence similarity 227 member B (508 aa)
           
  0.679
WDR70
WD repeat-containing protein 70; WD repeat domain containing; Belongs to the WD repeat GAD-1 family (654 aa)
       
 
  0.639
SMC5
Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies ( [...] (1101 aa)
     
   
  0.586
FAM214A
Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family (1083 aa)
     
   
  0.585
TSGA10IP
Testis specific 10 interacting protein (556 aa)
           
  0.584
OR8G1
Olfactory receptor 8G1; Odorant receptor; Olfactory receptors, family 8 (311 aa)
           
  0.582
NPIPB8
Nuclear pore complex interacting protein family member B8; Belongs to the NPIP family (432 aa)
           
  0.543
PAIP2B
Polyadenylate-binding protein-interacting protein 2B; Inhibits translation of capped and polyadenylated mRNAs by displacing PABPC1 from the poly(A) tail; Belongs to the PAIP2 family (123 aa)
           
  0.527
NOP9
Nucleolar protein 9; Armadillo-like helical domain containing (636 aa)
           
  0.526
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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