• Version:
  • 11.0 [archived version]
STRINGSTRING
TMEM158 TMEM158 MAML2 MAML2 FAM134C FAM134C GPR135 GPR135 ZNF665 ZNF665 C14orf37 C14orf37 ARHGAP15 ARHGAP15 C14orf105 C14orf105 TMEM229B TMEM229B SLC35F4 SLC35F4 KRTAP13-3 KRTAP13-3
"C14orf37" - Uncharacterized protein C14orf37 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C14orf37Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 (774 aa)    
Predicted Functional Partners:
C14orf105
Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105 (336 aa)
           
  0.658
ZNF665
Zinc finger protein 665; May be involved in transcriptional regulation; Zinc fingers C2H2-type (678 aa)
           
  0.632
SLC35F4
Solute carrier family 35 member F4; Putative solute transporter (521 aa)
           
  0.615
FAM134C
Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family (466 aa)
           
  0.558
KRTAP13-3
Keratin-associated protein 13-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (By similarity) (172 aa)
           
  0.533
TMEM229B
Transmembrane protein 229B (167 aa)
           
  0.533
MAML2
Mastermind-like protein 2; Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3; Belongs to the mastermind family (1156 aa)
           
  0.527
TMEM158
Transmembrane protein 158; Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide (300 aa)
           
  0.527
GPR135
Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans (494 aa)
           
  0.513
ARHGAP15
Rho GTPase-activating protein 15; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction; Pleckstrin homology domain containing (475 aa)
           
  0.497
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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