node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGAP15 | C14orf37 | ENSP00000295095 | ENSP00000267485 | Rho GTPase-activating protein 15; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction; Pleckstrin homology domain containing | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | 0.497 |
C14orf105 | C14orf37 | ENSP00000392368 | ENSP00000267485 | Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | 0.658 |
C14orf105 | SLC35F4 | ENSP00000392368 | ENSP00000342518 | Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105 | Solute carrier family 35 member F4; Putative solute transporter | 0.589 |
C14orf37 | ARHGAP15 | ENSP00000267485 | ENSP00000295095 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Rho GTPase-activating protein 15; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction; Pleckstrin homology domain containing | 0.497 |
C14orf37 | C14orf105 | ENSP00000267485 | ENSP00000392368 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105 | 0.658 |
C14orf37 | FAM134C | ENSP00000267485 | ENSP00000309432 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family | 0.558 |
C14orf37 | GPR135 | ENSP00000267485 | ENSP00000378548 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.513 |
C14orf37 | KRTAP13-3 | ENSP00000267485 | ENSP00000375109 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Keratin-associated protein 13-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (By similarity) | 0.533 |
C14orf37 | MAML2 | ENSP00000267485 | ENSP00000434552 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Mastermind-like protein 2; Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3; Belongs to the mastermind family | 0.527 |
C14orf37 | SLC35F4 | ENSP00000267485 | ENSP00000342518 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Solute carrier family 35 member F4; Putative solute transporter | 0.615 |
C14orf37 | TMEM158 | ENSP00000267485 | ENSP00000422431 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Transmembrane protein 158; Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide | 0.527 |
C14orf37 | TMEM229B | ENSP00000267485 | ENSP00000350050 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Transmembrane protein 229B | 0.533 |
C14orf37 | ZNF665 | ENSP00000267485 | ENSP00000379702 | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | Zinc finger protein 665; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.632 |
FAM134C | C14orf37 | ENSP00000309432 | ENSP00000267485 | Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | 0.558 |
FAM134C | ZNF665 | ENSP00000309432 | ENSP00000379702 | Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family | Zinc finger protein 665; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.543 |
GPR135 | C14orf37 | ENSP00000378548 | ENSP00000267485 | Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | 0.513 |
KRTAP13-3 | C14orf37 | ENSP00000375109 | ENSP00000267485 | Keratin-associated protein 13-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (By similarity) | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | 0.533 |
MAML2 | C14orf37 | ENSP00000434552 | ENSP00000267485 | Mastermind-like protein 2; Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3; Belongs to the mastermind family | Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37 | 0.527 |
MAML2 | TMEM158 | ENSP00000434552 | ENSP00000422431 | Mastermind-like protein 2; Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3; Belongs to the mastermind family | Transmembrane protein 158; Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide | 0.418 |
SLC35F4 | C14orf105 | ENSP00000342518 | ENSP00000392368 | Solute carrier family 35 member F4; Putative solute transporter | Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105 | 0.589 |